Exercise Biology: Signaling, Mechanisms and Benefits (Q1)
January 14-17, 2024  | Eldorado Hotel & Spa, Santa Fe, NM, United States
Jeffrey F. Horowitz, Laurie J. Goodyear and Karyn A. Esser
Scholarship Deadline: Oct. 24, 2023 | Abstract Deadline: Oct. 24, 2023 | Early Registration Deadline: Nov. 14, 2023
* Session Chair † Invited but not yet accepted | Program current as of August 23, 2025 4 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Sunday, January 14, 2024
4:00–8:00 PM Arrival and Registration Concourse
6:00–8:00 PM Welcome Mixer Cava Santa Fe
Monday, January 15, 2024
7:00–8:00 AM Breakfast Anasazi Ballroom
8:00–9:00 AM Welcome and Keynote Address Eldorado A
  * Jeffrey F. Horowitz, University of Michigan
Session Chair
 
  E. Dale Abel, David Geffen School of Medicine and UCLA Health
Mitochondria as Signaling Hubs
 
9:00–11:15 AM Improving the Health of the Next Generation: Epigenetic Effects of Maternal and Paternal Exercise on Offspring Eldorado A
  * E. Dale Abel, David Geffen School of Medicine and UCLA Health
Session Chair
 
  Laurie J. Goodyear, Joslin Diabetes Center, Harvard Medical School
Epigenetic Mechanisms Mediating the Beneficial Effects of Maternal Exercise on Offspring Metabolic Health
 
  Romain Barrès, CBMR & CNRS
Epigenetic Rewiring of Skeletal Muscle after Exercise Training
 
  Kristin I. Stanford, Ohio State University
Effects of Paternal Exercise on Offspring
 
  William Todd Cade, Duke University
Short Talk: Short Talk: Acute Effects of Aerobic and Resistance Exercise on Glucose Metabolism, Vascular Function and Plasma Metabolomics/Extracellular Vesicles During Pregnancy in Women with Obesity
 
9:30–9:50 AM Coffee Break Concourse
11:15–1:00 PM Poster Setup Anasazi Ballroom
11:15–5:00 PM On Own for Lunch
1:00–2:00 PM Career Roundtable (Joint) Eldorado A
  Wolfgang Liedtke, Regeneron Pharmaceuticals
Chair of Neurology, Psychiatry, Pain Medicine & Sensory Systems; Global Development
 
  Theanne N. Griffith, UC Davis
Assistant Professor
 
  Romain Barrès, CBMR & CNRS
Associate Professor
 
  Karen K. David, NINDS, National Institutes of Health
Program Director, NIH BRAIN Initiative
 
1:00–10:00 PM Poster Viewing Anasazi Ballroom
2:30–4:30 PM Workshop 1 Eldorado A
  * Laurie J. Goodyear, Joslin Diabetes Center, Harvard Medical School
Session Chair
 
  Curtis Hughey, University of Minnesota
Exercise Training Adaptations in Liver Glycogen and Glycerolipids Require Hepatic AMP-activated Protein Kinase in Mice
 
  Sebastian Salathe, University of Kansas Medical Center
Exercise Plus Time Restricted Feeding and Hepatic Ketogenesis Deficiency Upregulate Synaptogenesis Pathways in the Hippocampus of Mice
 
  Lisa Baer, The Ohio State University
Chronic Exercise Negates Concurrent High-Fat Diet to Improve Hepatic Metabolism and Regulates Medium Chain Acylcarnitine Handling
 
  Ruiqi Yang, University of Pittsburgh
Exercise Training Prevents Exosome-mediated Pre-metastatic Niche Formation in the Liver
 
  Cheehoon Ahn, University of Michigan
Years of Endurance Exercise Training Favorably Remodels Abdominal Subcutaneous Adipose Tissue in Adults with Overweight/obesity
 
  Pasquale Nigro, Joslin Diabetes Center
Exercise Training Regulates Long Noncoding RNAs Expression in Subcutaneous WAT of Obese Subjects
 
4:30–5:00 PM Coffee Available Concourse
5:00–7:00 PM The Far-Reaching Effects of Exercise Training - Exercise-Induced Changes in Liver, Microbiome, and White Adipose Tissue Eldorado A
  * Kristin I. Stanford, Ohio State University
Session Chair
 
  Mark A. Febbraio, Monash Institute of Pharmaceutical Sciences
Why is Exercise Medicine? Role of Exercise Extracellular Vesicles in Prevention of Disease
 
  Sara Campbell, Rutgers University
Exercise and the Gut Microbiome
 
  Jeffrey F. Horowitz, University of Michigan
Direct Effects of Exercise on Adipose Tissue Structure and Function
 
7:00–8:00 PM Social Hour with Lite Bites Anasazi Ballroom
7:30–10:00 PM Poster Session 1 Anasazi Ballroom
Tuesday, January 16, 2024
7:00–8:00 AM Breakfast Anasazi Ballroom
8:00–11:00 AM Clocks, Sleep and Exercise: Working Together for Health and Performance Eldorado A
  * Melissa Erickson, AdventHealth
Session Chair
 
  Gad Asher, Weizmann Institute of Science
Remote Presentation: Clock Proteins and Exercise Capacity
 
  Mark R Viggars, University of Florida
Short Talk: Remote Presentation: Short Talk: Muscle Clocks: Important Contributors to Systemic Exercise Adaptation
 
  Patrick Schrauwen, Maastricht
Circadian Rhythms in Human Metabolic Disease
 
  Karyn A. Esser, University of Florida
Scheduled Exercise as a Therapeutic approach for Muscle Health
 
  Maryam Safdar, Wayne State University School of Medicine
Short Talk: Short Talk: Genetic and Pharmacological Exercise Mimetics Rescue Endurance and Climbing Speed in Drosophila Clkout Mutants with Circadian Rhythm Disruption
 
9:00–9:20 AM Coffee Break Concourse
11:00–1:00 PM Poster Setup Anasazi Ballroom
11:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Anasazi Ballroom
4:30–5:00 PM Coffee Available Concourse
5:00–7:00 PM Health Benefits of Resistance Exercise: Hypertrophy and Beyond Eldorado A
  * Troy Hornberger, University of Wisconsin
Session Chair
 
  * Abigail Mackey, Bispebjerg Hospital
Session Chair
 
  Troy Hornberger, University of Wisconsin
Identifying the Signaling Events Through Which Resistance Exercise Induces Skeletal Muscle Growth
 
  Abigail Mackey, Bispebjerg Hospital
Plasticity of Human Skeletal Muscle and Myotendinous Junction
 
  Matthew Herring, University of Limerick
Impact of Resistance Exercise Training in the Treatment of Anxiety and Depression
 
  David J. Glass, Regeneron Pharmaceuticals, Inc.
Mechanisms that Effect Skeletal Muscle Function During Aging
 
7:00–8:00 PM Social Hour with Lite Bites Anasazi Ballroom
7:30–10:00 PM Poster Session 2 Anasazi Ballroom
Wednesday, January 17, 2024
7:00–8:00 AM Breakfast Anasazi Ballroom
8:00–11:00 AM Exercise and Modulation of Inflammatory Response Eldorado A
  * Mark A. Febbraio, Monash Institute of Pharmaceutical Sciences
Session Chair
 
  Jason Hellmann, University of Louisville
Adrenergic Regulation of the Pro-resolving Effects of Exercise and its Impact on Cardiometabolic Disease Prevention
 
  Kim Huffman, Duke University
Beneficial Effects of Exercise in Rheumatoid Arthritis
 
  Audrey Stone, University of Texas at Austin
Effects of Inflammatory Cytokines on Blood Flow Regulation during Exercise in Type 2 Diabetes
 
  Jennifer Darby, University of Pittsburgh
Short Talk: Short Talk: Exercise as Protective Training Against Trauma and Hemorrhagic Shock
 
  Jiannan Hu, Northwell Health
Short Talk: Short Talk: Exercise Drives an Anti-inflammatory Response in Interstitial Macrophages to Protect the Lung from Acute Inflammatory Injury
 
  Kent Langston, Harvard Medical School
Short Talk: Short Talk: Regulatory T Cells Shield Muscle Mitochondria from Interferon-mediated Damage to Promote the Beneficial Effects of Exercise
 
9:00–9:20 AM Coffee Break Concourse
11:00–5:00 PM On Own for Lunch
2:30–4:30 PM Workshop 2 Eldorado A
  * Karyn A. Esser, University of Florida
Session Chair
 
  Zhenxin Hou, Emory University
Exercise Training Alters Lipidomic Profiles of Plasma and Eight Tissues in Rats
 
  Jimmy Zhen, Stanford University
The MoTrPAC Data Hub: An Interactive Data Portal for Dissemination of MoTrPAC Data
 
  Malene E. Lindholm, Stanford University
The Mitochondrial Multi-omic Response to Exercise Training Across Rat Tissues
 
  Gina M. Many, Pacific Northwest National Laboratory
Sexual Dimorphism in the Multiomic Response to Endurance Exercise Training in Rat Subcutaneous White Adipose Tissue
 
  Lara Bideyan, UT Southwestern
Dissecting the Transcriptional Diversity of the Ventromedial Hypothalamus in Response to Exercise Training
 
  Theresia M. Schnurr, Stanford University
Harnessing Skeletal Muscle-specific Genetic Variation to Dissect Putative Causal Pathways Between Handgrip Strength and Cardiometabolic Phenotypes
 
4:30–5:00 PM Coffee Available Concourse
5:00–6:45 PM Mind Games: The Powerful impact of Exercise on the Brain Eldorado A
  * John P. Thyfault, University of Kansas Medical Center
Session Chair
 
  J. Carson Smith, University of Maryland
Neuroimaging Evidence for Exercise-Induced Neuroplasticity in Humans
 
  Constanza J. Cortes Rodriguez, University of Southern California
Neuroprotection on the Treadmill: New Insights into The Muscle-to-Brain Axis
 
  Cindy Barha, University of Calgary
Sex Differences in the Beneficial Effects of Exercise on Brain Function
 
  Autumn Ivy, UC Irvine
Short Talk: Short Talk: Neural Epigenetic Mechanisms of Early Life Adversity and Exercise Intervention
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Eldorado A
7:00–8:00 PM Social Hour with Lite Bites Anasazi Ballroom
8:00–11:00 PM Cash Bar Anasazi Ballroom
Thursday, January 18, 2024
7:00–11:59 PM Departure