Single Cell Biology: Expanding Potential Across Diseases (Q2)
January 1-4, 2027  | Location to be Determined
Jasmine Plummer and Musa M. Mhlanga
* Session Chair † Invited but not yet accepted | Program current as of August 23, 2025 4 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Friday, January 1, 2027
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Saturday, January 2, 2027
7:00–8:00 AM Breakfast
8:00–9:30 AM Welcome and Keynote Session (Joint)
  Matthias Mann †, Max Planck Institute of Biochemistry
Spatial Proteomics
 
  Orit Rozenblatt-Rosen †, Genentech
Sc/Spatial Methods to Characterize Cells and Tissues to Identify Targets and Next-Generation Biomarkers for Precision Medicine Treatments for Patients
 
9:30–9:50 AM Coffee Break
9:30–11:15 AM Advanced Technologies for Spatial Analyses (Joint)
  Joe Beechem †, NanoString Technologies
Subcellular Multiomic Imaging
 
  Brian D. Brown †, Mount Sinai School of Medicine
CRISPR and Spatial Omics
 
  Jasmine Plummer, St. Jude Children's Research Hospital
STAMP and Multimodal Omic Integration
 
  Short Talk(s) Chosen from Abstracts
 
11:15–12:15 PM Meet the Editors (Joint)
11:15–1:00 PM Poster Setup
11:15–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1: Novel Insights and Technologies in Single-Cell Analysis
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Single Cell & Spatial Biology: Applications to Disease
  Chris Marine †, VIB-KU Leuven
Skin and Cancer: Spatiotemporally Resolved Cellular Hierarchy in Melanoma Progression and Metastasis
 
  Karuna Ganesh †, Memorial Sloan Kettering Cancer Center
Organoid/Mouse: Patient-Derived Organoid and Mouse Models of Colorectal Cancer-Single Cell and Spatial Transcriptomic Profiling (Metastatic Stem Cell Identities)
 
  Michael P. Nyberg †, Novo Nordisk A/S
Cardiovascular Biology
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Sunday, January 3, 2027
7:00–8:00 AM Breakfast
8:00–11:00 AM Is Bigger Better?: Connecting Atlases to Relevant Translational Context
  Alexandra-Chloé Villani †, Broad Institute of MIT and Harvard
Big Atlas Efforts (HCA) of the Human Immune System
 
  Musa M. Mhlanga, Radboud Institute for Molecular Life Sciences
Spatial Omics for the Study of Innate Immune Memory in Large Cohorts
 
  Muzlifah A Haniffa †, Wellcome Sanger Institute
The Developing Human Immune System and Skin to Inform Stem Cell Therapy, Tissue Engineering and Adult Pathology
 
  Joe Poh Sheng Yeong †, Agency for Science, Technology and Research (A*STAR)
Using Spatial Omics in Large Cohorts to Understand Therapy Resistance (Breast, Colorectal and Liver Cancer)
 
9:00–9:20 AM Coffee Break
11:00–12:00 PM Panel Discussion 1: Integrating Single-Cell and Spatial Omics: Challenges and Solutions
12:00–1:00 PM Poster Setup
12:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
3:00–4:30 PM Career Roundtable
4:30–5:00 PM Coffee Available
5:00–7:00 PM New Technology & Computational Tools for Single Cell Biology
  Mostafa Ronaghi †, Cellanome
New Single Cell Profiling: What Does Full Omic Profiling in Live Cells Add to this Field
 
  Bianca Dumitrascu †, Columbia University
ML Models Derived from Single Cell Data for Representative Embryonic Development
 
  Christoph Bock †, CeMM & Medical University of Vienna
Computational Tools to Study the Role of Epigenetic Cell States in Immune Regulation in Rare Genetic Immunodeficiencies and Cancer
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Monday, January 4, 2027
7:00–8:00 AM Breakfast
8:00–11:00 AM Spatial Immunology (Joint)
  Ido Amit †, Weizmann Institute
The Power of One: Immunology in the Age of Single-Cell Genomics
 
  Ashley D Sanders †, MDC-BIMSB/BIH/Charité
Single Cell Genomics and Lineage Tracing (Crohn’s Disease, Colitis, Intestinal Inflammation)
 
  Renato Ostuni †, Ospedale San Raffaele S.r.l.
Molecular and Spatial Organization of Immune Microenvironments in Cancer
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–12:00 PM Panel Discussion 2: Single cell and Spatial Biology: Finding Focus Amid Rapid Progress
12:00–5:00 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: Advances in Spatial Omics and Microenvironmental Mapping
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM Single Cell and Spatial Biology Drivers of the Major DALYs
  Kayla Barnes †, Liverpool School of Tropical Medicine
Single-Cell Profiling of Infectious Disease (Malaria/Ebola) in LMICs
 
  Yukinori Okada †, Osaka University Graduate School of Medicine
Single Cell Genetics, Infectious and Autoimmune
 
  Li-Huei Tsai †, Massachusetts Institute of Technology
Single Cell Atlasing Reveals Program that is Associated with Cognitive Resilience to Alzheimer’s Disease Pathology
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
7:00–8:00 PM Social Hour with Dinner
8:00–11:00 PM Entertainment
8:00–11:00 PM Cash Bar
Tuesday, January 5, 2027
12:00–11:59 PM Departure