Proteomics for Translational and Precision Medicine (Q4)
January 1-5, 2028  | Location to be Determined
Christopher M. Rose
* Session Chair † Invited but not yet accepted | Program current as of October 10, 2026 12 PM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, May 1, 2028
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Tuesday, May 2, 2028
7:30–8:30 AM Breakfast
8:30–8:40 AM Welcome Remarks
8:40–9:30 AM Keynote Address (Joint)
  Steven P. Gygi †, Harvard Medical School
Proteomics Beyond the Reference Proteome: Identifying Non-Canonical Translation Products with Confidence
 
9:30–11:45 AM Uncovering the Hidden Proteome (Joint)
  Marie Anne Brunet †, Université de Sherbrooke
From Translation to Function: Discovering Functional Microproteins and Peptideins
 
  Sarah Slavoff †, Yale University
The Hidden Human Proteome: From Discovery to Molecular Function
 
  Francis O'Reilly †, St. Jude Childen's Research Hospital
Rigorous Proteomic Strategies for Mapping Protein Interactions and the Expanded Proteome
 
  Short Talk(s) Chosen from Abstracts
 
10:00–10:20 AM Coffee Break
11:45–12:45 PM Lunch
11:45–1:00 PM Poster Setup
11:55–12:55 PM Panel Discussion 1: When Is a Non-Canonical Protein Real? (Joint)
1:00–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1: Glycoproteomics for Biomarkers, Therapeutics, and Precision Medicine
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM AI, Multimodal Data Integration, and Computational Proteomics for Precision Medicine
  Claudia Langenberg †, Queen Mary University of London
From Circulating Proteins to Clinical Prediction: Computational Proteomics for Precision Medicine
 
  Olga Vitek †, Northeastern University
Integration of Language Models into Analysis of Proteomes
 
  Lindsay Pino †, Talus Bioscience, Inc
Learning the Ligandable Proteome: AI for Proteome-Scale Small-Molecule Discovery
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Wednesday, May 3, 2028
7:30–8:30 AM Breakfast
8:30–9:30 AM Keynote Address
  Melissa R. Miller †, Pfizer
UK Biobank: Population Proteomics of 600,000 Patients
 
9:30–9:50 AM Coffee Break
9:30–11:30 AM Biofluid Proteomics, High-Sensitivity Biomarkers, and Clinical Translation
  Nathan Basisty †, National Institutes of Health
Translational Geroproteomics: Circulating Biomarkers of Aging and Cellular Senescence
 
  Jennifer E. Van Eyk †, Cedars-Sinai
Clinical Translation of Circulating Proteome Biomarkers
 
  Jochen M. Schwenk, KTH - Royal Institute of Technology
Self-Sampled Proteome Dynamics
 
  Short Talk(s) Chosen from Abstracts
 
11:30–12:30 PM Lunch
11:30–1:00 PM Poster Setup
1:00–10:00 PM Poster Viewing
3:00–4:30 PM Career Roundtable
4:30–5:00 PM Coffee Available
5:00–7:00 PM Chemical, Functional, and Perturbation Proteomics for Target Discovery and Therapeutic Development
  Tiannan Guo †, Westlake University
Perturbation Proteomics-Based Virtual Cell Model
 
  Keriann Marie Backus †, David Geffen School of Medicine at UCLA
Covalent Chemoproteomics for Mapping the Ligandable Proteome and Therapeutic Discovery
 
  Christopher M. Rose, Genentech, Inc.
Proteomics-Guided Induced Proximity Therapeutics: From Mechanism of Action to Molecule Selection
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Thursday, May 4, 2028
7:30–8:30 AM Breakfast
8:30–11:30 AM Spatial, Cellular, and Surface Proteomics for Translational and Therapeutic Discovery
  Kathryn S. Lilley, University of Cambridge
Mapping the Dynamic Subcellular Proteome to Inform Cancer Therapeutic Strategies
 
  Emma K. Lundberg †, Stanford University and KTH Royal Institute of Technology
Generative Machine Learning Unlocks the First Proteome-Wide Image of Human Cells
 
  James A Wells †, University of California, San Francisco
Surfaceome Remodeling for Biomarker and Therapeutic Discovery
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:30–12:30 PM Lunch
2:30–4:30 PM Symposia Spotlight 2: Single-Cell, Low-Input, and Microscale Proteomics
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM The Hidden Proteome in Cancer: From Dark Antigens to Therapeutic Targets (Joint)
  Bing Zhang †, Vanderbilt University
Proteogenomic Landscapes of Cancer: Integrating Non-Canonical Translation into Tumor Biology
 
  Jyoti Choudhary †, Institute of Cancer Research
Mapping the Hidden Proteome: Proteogenomic Discovery of Non-Canonical Translation
 
  Steven A. Carr †, Broad Institute
Immunopeptidomics for Mapping Tumor-Specific Antigens
 
  Vinidhra Mani †, ProFound Therapeutics
Mining the Dark Proteome for New Therapeutic Targets
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions
6:55–7:00 PM Panel Discussion 2: From Discovery to Medicine: Moving Dark Proteins from the Lab to the Clinic.(Joint)
7:00–8:00 PM Social Hour with Dinner
8:00–11:00 PM Cash Bar
8:00–11:00 PM Entertainment
Friday, May 5, 2028
12:00–11:59 PM Departure