| 4:00–8:00 PM | Registration |
| 6:00–8:00 PM | Welcome Mixer |
| 7:30–8:30 AM | Breakfast |
| 8:30–8:40 AM | Welcome Remarks |
| 8:40–9:30 AM | Keynote Address (Joint) |
| Steven P. Gygi †, Harvard Medical School Proteomics Beyond the Reference Proteome: Identifying Non-Canonical Translation Products with Confidence |
| 9:30–11:45 AM | Uncovering the Hidden Proteome (Joint) |
| Marie Anne Brunet †, Université de Sherbrooke From Translation to Function: Discovering Functional Microproteins and Peptideins |
| Sarah Slavoff †, Yale University The Hidden Human Proteome: From Discovery to Molecular Function |
| Francis O'Reilly †, St. Jude Childen's Research Hospital Rigorous Proteomic Strategies for Mapping Protein Interactions and the Expanded Proteome |
| Short Talk(s) Chosen from Abstracts |
| 10:00–10:20 AM | Coffee Break |
| 11:45–12:45 PM | Lunch |
| 11:45–1:00 PM | Poster Setup |
| 11:55–12:55 PM | Panel Discussion 1: When Is a Non-Canonical Protein Real? (Joint) |
| 1:00–10:00 PM | Poster Viewing |
| 2:30–4:30 PM | Symposia Spotlight 1: Glycoproteomics for Biomarkers, Therapeutics, and Precision Medicine |
| Short Talks Chosen from Abstracts |
| 4:30–5:00 PM | Coffee Available |
| 5:00–7:00 PM | AI, Multimodal Data Integration, and Computational Proteomics for Precision Medicine |
| Claudia Langenberg †, Queen Mary University of London From Circulating Proteins to Clinical Prediction: Computational Proteomics for Precision Medicine |
| Olga Vitek †, Northeastern University Integration of Language Models into Analysis of Proteomes |
| Lindsay Pino †, Talus Bioscience, Inc Learning the Ligandable Proteome: AI for Proteome-Scale Small-Molecule Discovery |
| Short Talk(s) Chosen from Abstracts |
| 7:00–8:00 PM | Social Hour with Dinner |
| 7:30–10:00 PM | Posters |
| 7:30–8:30 AM | Breakfast |
| 8:30–9:30 AM | Keynote Address |
| Melissa R. Miller †, Pfizer UK Biobank: Population Proteomics of 600,000 Patients |
| 9:30–9:50 AM | Coffee Break |
| 9:30–11:30 AM | Biofluid Proteomics, High-Sensitivity Biomarkers, and Clinical Translation |
| Nathan Basisty †, National Institutes of Health Translational Geroproteomics: Circulating Biomarkers of Aging and Cellular Senescence |
| Jennifer E. Van Eyk †, Cedars-Sinai Clinical Translation of Circulating Proteome Biomarkers |
| Jochen M. Schwenk, KTH - Royal Institute of Technology Self-Sampled Proteome Dynamics |
| Short Talk(s) Chosen from Abstracts |
| 11:30–12:30 PM | Lunch |
| 11:30–1:00 PM | Poster Setup |
| 1:00–10:00 PM | Poster Viewing |
| 3:00–4:30 PM | Career Roundtable |
| 4:30–5:00 PM | Coffee Available |
| 5:00–7:00 PM | Chemical, Functional, and Perturbation Proteomics for Target Discovery and Therapeutic Development |
| Tiannan Guo †, Westlake University Perturbation Proteomics-Based Virtual Cell Model |
| Keriann Marie Backus †, David Geffen School of Medicine at UCLA Covalent Chemoproteomics for Mapping the Ligandable Proteome and Therapeutic Discovery |
| Christopher M. Rose, Genentech, Inc. Proteomics-Guided Induced Proximity Therapeutics: From Mechanism of Action to Molecule Selection |
| Short Talk(s) Chosen from Abstracts |
| 7:00–8:00 PM | Social Hour with Dinner |
| 7:30–10:00 PM | Posters |
| 7:30–8:30 AM | Breakfast |
| 8:30–11:30 AM | Spatial, Cellular, and Surface Proteomics for Translational and Therapeutic Discovery |
| Kathryn S. Lilley, University of Cambridge Mapping the Dynamic Subcellular Proteome to Inform Cancer Therapeutic Strategies |
| Emma K. Lundberg †, Stanford University and KTH Royal Institute of Technology Generative Machine Learning Unlocks the First Proteome-Wide Image of Human Cells |
| James A Wells †, University of California, San Francisco Surfaceome Remodeling for Biomarker and Therapeutic Discovery |
| Short Talk(s) Chosen from Abstracts |
| 9:30–9:50 AM | Coffee Break |
| 11:30–12:30 PM | Lunch |
| 2:30–4:30 PM | Symposia Spotlight 2: Single-Cell, Low-Input, and Microscale Proteomics |
| Short Talks Chosen from Abstracts |
| 4:30–5:00 PM | Coffee Available |
| 5:00–6:45 PM | The Hidden Proteome in Cancer: From Dark Antigens to Therapeutic Targets (Joint) |
| Bing Zhang †, Vanderbilt University Proteogenomic Landscapes of Cancer: Integrating Non-Canonical Translation into Tumor Biology |
| Jyoti Choudhary †, Institute of Cancer Research Mapping the Hidden Proteome: Proteogenomic Discovery of Non-Canonical Translation |
| Steven A. Carr †, Broad Institute Immunopeptidomics for Mapping Tumor-Specific Antigens |
| Vinidhra Mani †, ProFound Therapeutics Mining the Dark Proteome for New Therapeutic Targets |
| Short Talk(s) Chosen from Abstracts |
| 6:45–7:00 PM | Meeting Wrap-Up: Outcomes and Future Directions |
| 6:55–7:00 PM | Panel Discussion 2: From Discovery to Medicine: Moving Dark Proteins from the Lab to the Clinic.(Joint) |
| 7:00–8:00 PM | Social Hour with Dinner |
| 8:00–11:00 PM | Cash Bar |
| 8:00–11:00 PM | Entertainment |
| 12:00–11:59 PM | Departure |