Mitochondria: From Dysfunction to Disease (Q8)
January 1-5, 2028
| Location to be Determined
| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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| 8:00–8:10 AM |
Welcome Remarks |
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| 8:10–9:00 AM |
Keynote Address |
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Johan Auwerx †, École Polytechnique Fédérale de Lausanne
Targeting Mitochondrial Stress Responses: Terbinafine and Miglustat as Novel Lifespan and Healthspan |
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| 9:00–11:15 AM |
Mitochondrial Dysfunction in Aging and Aging-Associated Diseases |
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Marc Vermulst †, University of Southern California
Mitochondrial Function and Insulin-Like Growth Factor-1 Signaling in Lifespan |
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Vadim Gladyshev †, Brigham & Women's Hospital, Harvard Medical School
Role of Mitochondria, Redox Regulation, and Reactive Oxygen Species (ROS) in Aging and Cellular Rejuvenation |
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Mark S Kindy, University of South Florida
Mitochondria and Age-Related Diseases |
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David A Brown †, Mighty Therapeutics
Talk Title to be Announced |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
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| 11:25–12:25 PM |
Panel Discussion 1: DAMPS and Inflammation |
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| 12:25–1:00 PM |
Poster Setup |
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| 12:25–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Symposia Spotlight 1: Hot Topics: Cybrid Models, Brain Mapping |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Tissue Specific Mitochondrial Diversity, Genetics and Disease Implications |
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Martin Picard †, Columbia University
Mitochondrial Psychobiology and MitoBrainMap |
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Isha Jain †, Arc Institute and Gladstone/UCSF
Hypoxia in Primary Mitochondrial Disease |
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Navdeep S Chandel †, Northwestern University
Mitochondria Signaling in Physiology and Disease |
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Shamima Rahman †, University College London
Talk Title to be Announced |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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Tuesday, February 1, 2028
| 8:00–11:00 AM |
Structural Dynamics: Shape, Ultrastructure, and Quality Control |
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Gerald S. Shadel †, The Salk Institute for Biological Studies
Basic Biology of Mitochondria and mtDNA |
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Heidi M. McBride †, McGill University
Cell Biology of Mitochondrial Dysfunction to the Complex Pathogenesis of Motor Neuron and Other Degenerative Diseases |
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Antentor O Hinton Jr. †, Vanderbilt University School of Medicine
Mitochondrial Structure/Diversity |
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Sarah Cohen †, University of North Carolina-Chapel Hill
Organelle Communication Networks Rewire to Support Lipid Metabolism during Neuronal Differentiation |
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Short Talk(s) Chosen from Abstracts
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|
| 9:00–9:20 AM |
Coffee Break |
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| 11:00–1:00 PM |
Poster Setup |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 3:00–4:30 PM |
Career Roundtable |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Mitochondria Transfer and Transplantation Mechanisms |
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Simon Grelet †, University of Oklahoma
Nerve-to-Cancer Transfer of Mitochondria during Cancer Metastasis |
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Botond Roska †, Institute of Molecular and Clinical Ophthalmology (IOB) Basel
MitoCatch |
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Jonathan R. Brestoff, Washington University in St. Louis
Talk Title to be Announced |
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Noa Sher †, Minovia Therapeutics
Talk Title to be Announced |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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Wednesday, February 2, 2028
| 8:00–11:00 AM |
Mitochondrial DNA Editing: Fidelity, Heteroplasmy Control, and Translational Pipeline |
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David R. Liu †, Broad Institute, HHMI, and Harvard University
Mitochondrial Base Editors, Specifically DddA-Derived Cytosine Base Editors (DdCBEs) and TALE-Linked Deaminases (TALEDs) |
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Jin-Soo Kim †, Korea Advanced Institute for Science and Technology
Revolutionary Mitochondrial Genome Editing Tools |
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Michal Minczuk †, University of Cambridge
Mitochondrial-Targeted ZFNs (mtZFNs) and TALENs for Eliminating Mutant mtDNA |
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Samantha C Lewis †, University of California, Berkeley
Self-Renewal of Neuronal Mitochondria through Asymmetric Division |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:10–12:10 PM |
Panel Discussion 2: Targeting Oxidative Stress & Redox |
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| 12:10–5:00 PM |
On Own for Lunch |
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| 2:30–4:30 PM |
Symposia Spotlight 2: Mito–Lipid Crosstalk and Membrane Remodeling |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–6:45 PM |
Mitochondrial Metabolic Flexibility and Disease |
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Edward T. Chouchani †, Dana-Farber Cancer Institute
Mechanisms of Mitochondrial Reactive Oxygen Species (mROS) Production and Developing Targeted Compounds for Metabolic Disease Rather than General Antioxidants |
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Jodi Nunnari, Altos Labs (& University of California - Davis)
A Leading Expert in Mitochondrial Dynamics, Membrane Architecture, and the Protein-Lipid Interactions Regulating Cristae Structure |
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Anu Suomalainen Wartiovaara †, University of Helsinki
Mitochondrial DNA Maintenance and its Role in Metabolic Disorders and Mitochondrial Respiratory Chain Disorders |
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Ana Victoria Lechuga-Vieco †, Institute for Research in Biomedicine Barcelona
Talk Title to be Announced |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 PM |
Entertainment |
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Thursday, February 3, 2028
