Aging: Defining Functional Decline, Uncovering Mechanisms, Advancing Therapies (R1)
March 5-8, 2028  | Fairmont Hotel Vancouver, Vancouver, BC, Canada
* Session Chair † Invited but not yet accepted | Program current as of September 25, 2026 1 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Sunday, March 5, 2028
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Monday, March 6, 2028
7:30–8:30 AM Breakfast
8:30–8:40 AM Welcome Remarks
8:40–9:30 AM Keynote Address
  Tony Wyss-Coray †, Stanford University School of Medicine
Blood Factors, Brain Aging, and Resilience
 
9:30–11:45 AM Defining Aging: Biomarkers and Function
  Luigi Ferrucci †, NIA, National Institutes of Health
Biomarkers and Functional Trajectories of Human Aging
 
  Guido Kroemer †, Cordeliers Research Center
Autophagy as a Biomarker and Effector of Healthy Aging
 
  Amos Baruch †, Calico Life Sciences
Biomarker Strategies for Translational Aging Research
 
  Pauline Maki †, University of Illinois at Chicago
Sex-Specific Trajectories of Aging and Function
 
  Short Talk(s) Chosen from Abstracts
 
10:00–10:20 AM Coffee Break
11:45–1:00 PM Poster Setup
11:45–2:30 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1: Inflammaging: Immune Dysfunction, Tissue Crosstalk, and Age-Related Inflammation
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Immune Decline and Inflammaging
  Maxim Artyomov †, Washington University in St. Louis
Immune Aging at Single-Cell Resolution
 
  Jorg J. Goronzy †, Mayo Clinic
T Cell Aging and Immune Fitness Across the Lifespan
 
  Daniel Puleston †, Icahn School of Medicine at Mount Sinai
Metabolic Control of Macrophage Aging
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Tuesday, March 7, 2028
7:30–8:30 AM Breakfast
8:00–8:30 AM Poster Setup
8:15–5:00 PM Poster Viewing
8:30–11:30 AM Tissue Plasticity, Repair, and Rejuvenation
  Farners Amargant i Riera †, Washington University in St. Louis
Mechanical Regulation of Ovarian Aging and Follicle Function
 
  Chanhee Kang †, Seoul National University
Senescence, Autophagy, and Stress Responses in Aging
 
  Emi K. Nishimura †, University of Tokyo
Stem Cell Aging and Skin Regeneration
 
  Pura Muñoz Cánoves †, Altos Labs
Muscle Stem Cell Aging and Rejuvenation
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:30–12:30 PM Lunch
12:00–2:30 PM Posters
3:00–4:30 PM Career Roundtable
4:30–5:00 PM Coffee Available
5:00–7:00 PM Cancer Aging
  Emmanuelle Passegué †, Columbia University
Aging of Hematopoiesis and Cancer Susceptibility
 
  Eric Gilson †, Université de Lyon
Telomere Dysfunction, Senescence, and Cancer in Aging
 
  Miriam Merad, Mount Sinai School of Medicine
Aging and the Tumor Microenvironment
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM On Own for Dinner
Wednesday, March 8, 2028
7:30–8:30 AM Breakfast
8:30–11:30 AM Mitochondrial Competence and Decline in Aging
  Marcia C. Haigis †, Harvard Medical School
Mitochondrial Signaling in Aging and Age-Related Disease
 
  Aleksandra Trifunovic †, University of Cologne
Stress Responses to Mitochondrial Dysfunction in Aging
 
  Ying Liu †, Peking University
Mitochondrial Stress Signaling and Adaptive Resilience
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:30–2:30 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: Measuring Aging Decline: Biomarkers, Functional Readouts, and Biological Age
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM Translational Models and Gerotherapeutics
  Linda Partridge †, University College London
From Aging Mechanisms to Geroprotective Interventions
 
  Paul Robbins †, University of Minnesota
Cellular Senescence and Senotherapeutic Strategies
 
  David J. Glass, Regeneron Pharmaceuticals, Inc.
Translating Aging Biology into Therapeutic Development
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
7:00–8:00 PM Social Hour with Dinner
8:00–11:00 PM Entertainment
8:00–11:00 PM Cash Bar
Thursday, March 9, 2028
12:00–11:59 PM Departure