Cancer Immunotherapy: New Pathways and Innovating Therapeutics (R3)
January 1-5, 2028  | Location to be Determined
Niroshana Anandasabapathy
* Session Chair † Invited but not yet accepted | Program current as of October 11, 2026 5 PM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, January 17, 2028
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Tuesday, January 18, 2028
7:00–8:00 AM Breakfast
8:00–8:10 AM Welcome Remarks
8:10–9:00 AM Keynote Address
  Fred J. Ramsdell †, Sonoma Biotherapeutics
Why I Won the Nobel Prize, and the Relevance to Cancer Immunotherapy
 
9:00–11:15 AM Frankensteining the Future: Transformative Technologies, Next Generation Screens, and AI-based Responses
  Benjamin Izar †, Columbia Universtiy Medical Center
Base Editing Screens Advancing IO
 
  Aviv Regev †, Genentech
The future of IO
 
  Ashley Lakner †, Roche
Directing Early-Stage Discovery Pipelines Focused on Novel Cancer Immunotherapies
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:25–12:25 PM Panel Discussion and Debate 1: Spectacular Failures and what we Learned: Why have Checkpoints Failed Beyond PD1; CAR Failures and what was Learned
12:25–1:30 PM Poster Setup
12:25–5:00 PM On Own for Lunch
1:30–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1: Novel Antigen Targets for ADC and T Cell Engager
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM New Antigen Spaces, Immune Editing, and the Bystander Crowd
  Yardena Samuels, Weizmann Institute of Science
Neoantigens in Cancer
 
  Evan W. Newell †, Fred Hutchinson Cancer Research Center
The Bystander Effect, Viral Responses Shaping Tumor Immunity
 
  Short Talk(s) Chosen from Abstracts
 
  Özlem Türeci †, BioNTech
Transformative Vaccine Strategies for Cancer Care
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Wednesday, January 19, 2028
7:00–8:00 AM Breakfast
8:00–11:00 AM Spectacular Wins and Failures in IO: Lessons Learned and Alternative Paths
  Saar I. Gill †, University of Pennsylvania
Balancing Failures with New Directions: What Works and Why?
 
  Jennifer Ann Wargo †, University of Texas MD Anderson Cancer Center
Microbiome and Cancer: The Bumpy Road to Success
 
  Jedd D. Wolchok †, Weill Cornell Medicine
The Bermuda Triangle of IO: TIGIT, IDO, LAG3
 
  Yvonne Y. Chen †, University of California, Los Angeles
Biomolecular Engineering and Synthetic Biology Approaches to Enhance CARs
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–1:00 PM Poster Setup
11:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
3:00–4:30 PM Career Roundtable
4:30–5:00 PM Coffee Available
5:00–7:00 PM IO DJs: Modulating Innate and Adaptive Immune Circuits
  Ana Carrizosa Anderson †, Harvard Medical School
Emerging T Cell Targets from Basic Discovery
 
  Andrea Schietinger †, Memorial Sloan Kettering Cancer Center
Tumor Immune Triads
 
  Paul G. Thomas †, Fred Hutchinson Cancer Center
What Really Dictates Successful Immunity to Flu and Cancer
 
  Thorsten R. Mempel †, Massachusetts General Hospital
Homing, Chemokines, and Trafficking Tumor Immunity
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Thursday, January 20, 2028
7:00–8:00 AM Breakfast
8:00–11:00 AM Translating Myeloid Biology to New Targets, and Alternatives
8:00–11:00 AM Panel Discussion and Debate 2: Suboptimal Priming vs. Hostile TME. TAA/Neoantigen/Bystander: What Really Matters and Why?
  David Sancho †, Centro Nacional de Investigaciones Cardiovasculares, CNIC
Tumor Immune Escape, Targeting Immunosuppressive Macrophages, and Alternatives
 
  Mikael J Pittet †, University of Geneva
Pivoting from Macrophage Targets to CCR7+ Migratory DC in Cancer
 
  Niroshana Anandasabapathy, Weill Cornell Medicine
Drivers of Immune Related Adverse Events: A Failure in IO or a Spectacular Success?
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–5:00 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: Tumor Immune Resistance
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM Immune Set Points in Cancer
  Charles G. Drake, Johnson and Johnson
New Pharma Approaches
 
  Kole T. Roybal †, University of California, San Francisco
Cellular Engineering, Translation, and Paving the Way to Industry
 
  Haydn Kissick †, Emory University
Setpoints Driving TCF7, Immune Memory, and Successful IO Responses
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions
7:00–8:00 PM Social Hour with Dinner
8:00–11:00 PM Entertainment
8:00–11:00 PM Cash Bar
Friday, January 21, 2028
12:00–11:59 PM Departure