Tumor Metabolism: Novel Pathways and Therapeutic Challenges (R4)
January 1-5, 2028
| Location to be Determined
Matthew G Vander Heiden, Daniel E. Frigo and Lydia Finley
Saturday, January 1, 2028
| 1:00–6:00 PM |
Registration |
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| 3:00–3:10 PM |
Welcome Remarks |
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| 3:10–4:00 PM |
Keynote Address |
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Ralph J DeBerardinis †, University of Texas Southwestern Medical Center Cancer as a Systemic Metabolic Disease |
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| 4:00–6:00 PM |
Metabolites as Signaling Molecules to Influence Cancer |
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Kathryn E. Wellen †, University of Pennsylvania How Environmental Metabolite Availability Shapes Gene Regulation |
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Navdeep S Chandel †, Northwestern University Systemic Impact of Metabolites |
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Lydia Finley, Memorial Sloan Kettering Cancer Center Decoding Metabolic Signals during Cell Fate Transitions |
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Short Talk(s) Chosen from Abstracts
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| 6:00–8:00 PM |
Welcome Reception |
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| 12:25–1:00 PM |
Poster Setup |
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| 8:00–11:15 AM |
New Insights into Metabolic Pathways |
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Gina M DeNicola †, Moffitt Cancer Center Impact of Metals on Pathways |
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Arkaitz Carracedo †, Center for Cooperative Research in Biosciences Emerging Intersections between Metabolism and Signaling |
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Lucas B. Sullivan †, Fred Hutchinson Cancer Research Center Novel Mass Spectrometry Methods to Study Cysteine Metabolism and the Impact on Drug Response |
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Gerta Hoxhaj †, UT Southwestern Medical Center Novel Regulation of Cancer Cell Metabolism |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
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| 11:25–12:25 PM |
Meet-the-Editor |
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| 12:25–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Symposia Spotlight 1: Systemic Metabolism |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Altered Organellar Metabolism in Cancer |
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Payam Anthony Gammage †, Cancer Research UK Scotland Institute How Mitochondria Shape Immune Responses in Cancer |
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Kivanc Birsoy †, Rockefeller University Approaches to Study Organelle Metabolite Transport |
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Jared Rutter †, University of Utah Pathway Regulation by Organellar Metabolites |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Impact of the Microenvironment on Tumor Metabolism |
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Alexander Muir †, University of Chicago Influence of Environmental Metabolites on Cancer Phenotypes |
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Sarah-Maria Fendt †, VIB-KU Leuven Local and Systemic Metabolic Influences on Metastasis |
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Wilhelm Palm †, German Cancer Reserach Center Cancer Cell Scavenging from the Environment |
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Jessalyn M. Ubellacker †, Harvard T.H. Chan School of Public Health The Impact of Regional Metabolic Environments on Immunological Control of Tumor Growth |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–1:00 PM |
Poster Setup |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 3:00–4:30 PM |
Career Roundtable |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Metabolic Drivers of Tumor Evolution |
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Maria Rodriguez Colman †, UMC Utrecht Use of Metabolite Sensors to Assess Redox Regulation of Cancer Phenotypes |
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Christian Frezza †, University of Cologne From Genotype to Metabolic Phenotype: Multi-Omic Approaches to Cancer Evolution |
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Matthew G Vander Heiden, Massachusetts Institute of Technology Impact of Metabolism on Cancer Heterogeneity |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Intersections between Tumor and Host |
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Rachel J. Perry †, Yale University How Host Metabolism Shapes Tumor Metabolism |
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Liza Makowski †, The Ohio State University Impact of Surgical and Pharmacological Weight Loss on Cancer |
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Daniel J. Drucker †, Lunenfeld-Tanenbaum Research Institute GLP-1 Medicines: Emerging Opportunities in Cancer Prevention and Therapy |
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Thales Papagiannakopoulos †, Salk Institute for Biological Studies How Cancer-Nerve Interactions Influence Host Metabolism |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 2:30–4:30 PM |
Symposia Spotlight 2 |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–6:45 PM |
Metabolic Considerations for Successful Cancer Therapy |
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Daniel E. Frigo, University of Texas MD Anderson Cancer Center Targeting Prostate Cancer Metabolism Across Shifting Endocrine States |
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Costas A. Lyssiotis †, University of Michigan Treating Cancer by Targeting Salvage Metabolism |
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Karen H. Vousden †, Francis Crick Institute Systemic Metabolic Approaches to Target Cancer |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 PM |
Entertainment |
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Thursday, January 6, 2028