Islet Biology in Health and Stress (R5)
April 3-6, 2028
| Keystone Resort, Keystone, CO, United States
| 4:00–8:00 PM | Registration |
| 6:00–8:00 PM | Welcome Mixer |
| 7:00–8:00 AM | Breakfast |
| 8:00–8:10 AM | Welcome Remarks |
| 8:10–9:00 AM | Keynote Address |
| Yuval Dor †, Hebrew University-Hadassah Medical School RNA Editing and Islet Immunogenicity |
| 9:00–11:15 AM | Beta Cell Stress: Adaptation, Death, or Identity Loss |
| Cristina Aguayo-Mazzucato †, Joslin Diabetes Center Beta Cell Senescence in Type 2 Diabetes |
| Aleksey Matveyenko †, Mayo clinic Circadian Clock Control of Beta Cell Health |
| Doris A. Stoffers †, Perelman School of Medicine, University of Pennsylvania Fine Tuning of Beta Cell UPR |
| Short Talk(s) Chosen from Abstracts |
| 9:30–9:50 AM | Coffee Break |
| 11:15–1:00 PM | Poster Setup |
| 11:15–5:00 PM | On Own for Lunch |
| 1:00–10:00 PM | Poster Viewing |
| 2:30–4:30 PM | Symposia Spotlight 1 |
| Short Talks Chosen from Abstracts |
| 4:30–5:00 PM | Coffee Available |
| 5:00–7:00 PM | Beta Cell Vulnerability to Stress: Intrinsic Fragility and Intercellular Crosstalk |
| Raghavendra G Mirmira †, The University of Chicago Islet Intrinsic Proinflammatory Signaling in T1D |
| Sangeeta Dhawan, City of Hope Beta Cell Genomic Fragility in Development and Disease |
| Yasaman Aghazadeh †, Montreal Clinical Research Institute Islet Vascular Niche and Beta cell Health and Resilience |
| Short Talk(s) Chosen from Abstracts |
| 7:00–8:00 PM | Social Hour with Dinner |
| 7:30–10:00 PM | Posters |
| 7:00–8:00 AM | Breakfast |
| 8:00–11:00 AM | Organelle Dysfunction and Beta Cell Fate |
| Scott A Soleimanpour, University of Michigan Medical School Mitochondrial Protein Misfolding and Beta Cell Failure in Diabetes |
| Feyza Engin, University of Wisconsin-Madison Beta Cell Stress and Immune Communication |
| Dan S. Luciani †, University of British Columbia Beta Cell Lysosomes in T1D |
| Erica Cai †, Indiana University Genome-Scale Screening and CRISPR Gene-Editing to Investigate beta Cell Fate |
| Short Talk(s) Chosen from Abstracts |
| 9:00–9:20 AM | Coffee Break |
| 11:00–1:00 PM | Poster Setup |
| 11:00–5:00 PM | On Own for Lunch |
| 1:00–10:00 PM | Poster Viewing |
| 3:00–4:30 PM | Career Roundtable |
| 4:30–5:00 PM | Coffee Available |
| 5:00–7:00 PM | Cellular and Molecular Consequences of Stress |
| Zong Wei †, Mayo Clinic Dynamic Control of Beta Cell Enhancer States in Metabolic Stress |
| Miriam Cnop †, Universite Libre de Bruxelles ER Stress, Insulin Biogenesis, and Monogenic Diabetes |
| Pedro Herrera †, University of Geneva Islet Transdifferentiation and Plasticity |
| Short Talk(s) Chosen from Abstracts |
| 7:00–8:00 PM | Social Hour with Dinner |
| 7:30–10:00 PM | Posters |
| 7:00–8:00 AM | Breakfast |
| 8:00–11:00 AM | Systems Approaches to Understand Beta Cell Stress Responses |
| Kyle Gaulton †, University of California, San Diego Functional Genomics of Beta Cell ER Stress and Type 2 Diabetes Risk |
| Shuibing Chen †, Weill Cornell Medical College Multimodal Approaches to Identify Factors Underlying Beta Cell Vulnerability and Type 1 Diabetes Risk |
| Ernesto Satoshi Nakayasu †, Pacific Northwest National Laboratory Proteomics and Proteogenomics Mapping of Islet Inflammatory Response |
| Short Talk(s) Chosen from Abstracts |
| 9:00–9:20 AM | Coffee Break |
| 11:00–5:00 PM | On Own for Lunch |
| 2:30–4:30 PM | Symposia Spotlight 2 |
| Short Talks Chosen from Abstracts |
| 4:30–5:00 PM | Coffee Available |
| 5:00–6:45 PM | From Islets to Impact: Translating Innovation into Diabetes Therapies |
| Alexandra Title, InSphero AG New Approaches for Diabetes Modeling |
| Gopika Nair †, Eli Lilly Recreating Islet Development to Build Better Beta Cells for in vivo Translation |
| Patrick Collombat †, INSERM and DiogenX Wnt/beta Catenin Signaling to Generate Insulin Producing beta Cells |
| Tristan Thwaites †, AspectBio Engineering Stem Cell Derived Islets for Cell Therapies in T1D |
| Michael L. Stitzel †, The Jackson Laboratory for Genomic Medicine Single-Cell Biology of Beta Cell Failure in Metabolic Stress and Type 2 Diabetes |
| Short Talk(s) Chosen from Abstracts |
| 6:45–7:00 PM | Meeting Wrap-Up: Outcomes and Future Directions |
| 7:00–8:00 PM | Social Hour with Dinner |
| 8:00–11:00 PM | Entertainment |
| 8:00–11:00 PM | Cash Bar |
| 12:00–11:59 PM | Departure |