Islet Biology in Health and Stress (R5)
January 1-5, 2028
| Location to be Determined
Saturday, January 1, 2028
| 4:00–8:00 PM |
Registration |
|
| 6:00–8:00 PM |
Welcome Mixer |
|
| 8:00–8:10 AM |
Welcome Remarks |
|
| 8:10–9:00 AM |
Keynote Address |
|
| |
Yuval Dor †, Hebrew University-Hadassah Medical School
RNA Editing and Islet Immunogenicity |
|
| 9:00–11:15 AM |
Beta Cell Stress: Adaptation, Death, or Identity Loss |
|
| |
Cristina Aguayo-Mazzucato †, Joslin Diabetes Center
Beta Cell Senescence in Type 2 Diabetes |
|
| |
Aleksey Matveyenko †, Mayo clinic
Circadian Clock Control of Beta Cell Health |
|
| |
Doris A. Stoffers †, Perelman School of Medicine, University of Pennsylvania
Fine Tuning of Beta Cell UPR |
|
| |
Short Talk(s) Chosen from Abstracts
|
|
| 9:30–9:50 AM |
Coffee Break |
|
| 11:15–1:00 PM |
Poster Setup |
|
| 11:15–5:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
|
| 2:30–4:30 PM |
Symposia Spotlight 1 |
|
| |
Short Talks Chosen from Abstracts
|
|
| 4:30–5:00 PM |
Coffee Available |
|
| 5:00–7:00 PM |
Beta Cell Vulnerability to Stress: Intrinsic Fragility and Intercellular Crosstalk |
|
| |
Raghavendra G Mirmira †, The University of Chicago
Islet Intrinsic Proinflammatory Signaling in T1D |
|
| |
Sangeeta Dhawan, City of Hope
Beta Cell Genomic Fragility in Development and Disease |
|
| |
Yasaman Aghazadeh †, Montreal Clinical Research Institute
Islet Vascular Niche and Beta cell Health and Resilience |
|
| |
Short Talk(s) Chosen from Abstracts
|
|
| 7:00–8:00 PM |
Social Hour with Dinner |
|
| 8:00–11:00 AM |
Organelle Dysfunction and Beta Cell Fate |
|
| |
Scott A Soleimanpour, University of Michigan Medical School
Mitochondrial Protein Misfolding and Beta Cell Failure in Diabetes |
|
| |
Feyza Engin, University of Wisconsin-Madison
Beta Cell Stress and Immune Communication |
|
| |
Dan S. Luciani †, University of British Columbia
Beta Cell Lysosomes in T1D |
|
| |
Erica Cai †, Indiana University
Genome-Scale Screening and CRISPR Gene-Editing to Investigate beta Cell Fate |
|
| |
Short Talk(s) Chosen from Abstracts
|
|
| 9:00–9:20 AM |
Coffee Break |
|
| 11:00–1:00 PM |
Poster Setup |
|
| 11:00–5:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
|
| 3:00–4:30 PM |
Career Roundtable |
|
| 4:30–5:00 PM |
Coffee Available |
|
| 5:00–7:00 PM |
Cellular and Molecular Consequences of Stress |
|
| |
Zong Wei †, Mayo Clinic
Dynamic Control of Beta Cell Enhancer States in Metabolic Stress |
|
| |
Miriam Cnop †, Universite Libre de Bruxelles
ER Stress, Insulin Biogenesis, and Monogenic Diabetes |
|
| |
Pedro Herrera †, University of Geneva
Islet Transdifferentiation and Plasticity |
|
| |
Short Talk(s) Chosen from Abstracts
|
|
| 7:00–8:00 PM |
Social Hour with Dinner |
|
| 8:00–11:00 AM |
Systems Approaches to Understand Beta Cell Stress Responses |
|
| |
Kyle Gaulton †, University of California, San Diego
Functional Genomics of Beta Cell ER Stress and Type 2 Diabetes Risk |
|
| |
Shuibing Chen †, Weill Cornell Medical College
Multimodal Approaches to Identify Factors Underlying Beta Cell Vulnerability and Type 1 Diabetes Risk |
|
| |
Ernesto Satoshi Nakayasu †, Pacific Northwest National Laboratory
Proteomics and Proteogenomics Mapping of Islet Inflammatory Response |
|
| |
Short Talk(s) Chosen from Abstracts
|
|
| 9:00–9:20 AM |
Coffee Break |
|
| 11:00–5:00 PM |
On Own for Lunch |
|
| 2:30–4:30 PM |
Symposia Spotlight 2 |
|
| |
Short Talks Chosen from Abstracts
|
|
| 4:30–5:00 PM |
Coffee Available |
|
| 5:00–6:45 PM |
From Islets to Impact: Translating Innovation into Diabetes Therapies |
|
| |
Alexandra Title, InSphero AG
New Approaches for Diabetes Modeling |
|
| |
Gopika Nair †, Eli Lilly
Recreating Islet Development to Build Better Beta Cells for in vivo Translation |
|
| |
Patrick Collombat †, INSERM and DiogenX
Wnt/beta Catenin Signaling to Generate Insulin Producing beta Cells |
|
| |
Tristan Thwaites †, AspectBio
Engineering Stem Cell Derived Islets for Cell Therapies in T1D |
|
| |
Michael L. Stitzel †, The Jackson Laboratory for Genomic Medicine
Single-Cell Biology of Beta Cell Failure in Metabolic Stress and Type 2 Diabetes |
|
| |
Short Talk(s) Chosen from Abstracts
|
|
| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
|
| 7:00–8:00 PM |
Social Hour with Dinner |
|
| 8:00–11:00 PM |
Entertainment |
|
Wednesday, January 5, 2028
