MASH: A Central Player in the Cardiovascular-Kidney-Liver Metabolic Syndrome (R7)
January 1-5, 2028  | Location to be Determined
Bart Staels
* Session Chair † Invited but not yet accepted | Program current as of September 23, 2026 2 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Saturday, January 1, 2028
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Sunday, January 2, 2028
12:25–1:00 PM Poster Setup
7:00–8:00 AM Breakfast
8:00–8:10 AM Welcome Remarks
8:10–9:00 AM Keynote Address
  Arun J. Sanyal †, Virginia Commonwealth University Medical Center
MASH as a Systemic Disease Across the Cardiovascular-Kidney-Metabolic Continuum
 
9:00–11:15 AM MASH as a Multisystem Disease - Whole-Patient Clinical Integration and Human Genetics
  Alina M. Allen, Mayo Clinic
The Liver in CKLM
 
  Giovanni Targher †, University of Verona
Whole-Patient Cardiovascular and Extra-hepatic Cancers in MASH
 
  Katherine R. Tuttle †, University of Washington
The Kidney in CKLM
 
  Luca Lotta †, Regeneron Pharmaceuticals Inc.
Human Genetics to Identify Shared Targets Across MASH and Cardiovascular-Kidney-Metabolic Disease
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:25–12:25 PM Meet-the-Editor
12:25–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Mechanisms of Inter-Organ Crosstalk in MASH and CKLM
  Jia-Horng Kao, National Taiwan University
Infection Interaction with MASLD and CKLM Outcomes in Viral Hepatitis
 
  Neil C. Henderson †, Institute of Regeneration and Repair, University of Edinburgh
Shared Fibrotic Programs Across the Liver, Heart and Kidney in MASH
 
  Yonglun Luo †, Aarhus University
Endothelial Dysfunction as an Inter-Organ Mechanism in MASH and CKLM
 
  Florian Kahles †, University Hospital RWTH Aachen
Inflammation as a Unifying Mechanism in MASH and CKLM
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Monday, January 3, 2028
7:00–8:00 AM Breakfast
8:00–11:00 AM Metabolic and Cardio-Renal-Liver Axes in MASH
  Lale Ozcan †, Columbia University
The Liver in the Inter-Organ Cross-Talk from Pre-Diabetes to Diabetes
 
  Kai-Chien Yang, National Taiwan University
Liver Cross-Talk with the Cardiovascular System
 
  Katalin Susztak †, University of Pennsylvania
Liver-Kidney Cross-Talk in CKLM
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–1:00 PM Poster Setup
11:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
3:00–4:30 PM Career Roundtable
4:30–5:00 PM Coffee Available
5:00–7:00 PM Gut-Liver-Adipose Signaling in MASH and CKLM
  Susanne Mandrup †, University of Southern Denmark
Liver-Adipose Tissue Cross-Talk Mechanisms
 
  Rebecca A Haeusler †, Columbia University
Liver-Intestine Communication in CKLM
 
  Harry Sokol †, Saint-Antoine Hospital
Gut Microbiota and Hepatic Inflammation in CKLM
 
  Takahiro Ochiya †, Tokyo Medical University
Hepatic Exosomes in CKLM
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Tuesday, January 4, 2028
7:00–8:00 AM Breakfast
8:00–11:00 AM Human-Relevant Models, Multi-Omics, and AI for MASH Across Organ Systems
  Vincent WS Wong †, Chinese University of Hong Kong
Non-Invasive Tests to Assess Liver Dysfunction and Multi-Organ Failure in CKLM
 
  Joseph C. Wu †, Stanford University
Organoids / Organ-on-Chip: in vitro Modeling of Liver-Heart-Kidney Crosstalk
 
  Karin Conde-Knape †, Valo Health
AI to Accelerate Drug Development Acting on Multi-Organs in CKLM
 
  Bart Staels, Institut Pasteur de Lille, Université Lille
Experimental Models of Obesity, Metabolic Liver and Cardiovascular Disease
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–5:00 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM Therapeutic Translation to Address Multi-Organ Disease in MASH and CKLM
  Ruth E. Gimeno †, Eli Lilly and Company
Role of Incretins in CKLM
 
  Timothy P Rolph †, Akero Therapeutics
FGF21 in CKLM
 
  Rebecca A. Taub †, Madrigal Pharmaceuticals
Targeting Thyroid Hormone Receptors in MASH with Impact on CKM
 
  Lakshmi Santhanam †, Johns Hopkins University
Tissue-Selective Drug Delivery
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions
7:00–8:00 PM Social Hour with Dinner
8:00–11:00 PM Cash Bar
8:00–11:00 PM Entertainment
Wednesday, January 5, 2028
12:00–11:59 PM Departure