Neurodevelopmental Disorders: Mechanisms and Therapeutics (S4)
January 1-4, 2027
| Location to be Determined
Tomasz Nowakowski, Xin Jin, Stephan Sanders and Zhaolan (Joe) Zhou
4:00–8:00 PM |
Registration |
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6:00–8:00 PM |
Welcome Mixer |
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Saturday, January 2, 2027
8:00–9:00 AM |
Welcome and Keynote Address |
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Huda Y. Zoghbi †, Baylor College of Medicine A Journey in Rett Syndrome: From Basic Science Discovery of Causal Gene to Therapies of Patients |
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9:00–11:15 AM |
Genetics and Genomics of Neurodevelopmental Disorders |
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Hyejung Won †, University of North Carolina, Chapel Hill Testic Causal Hypothesis of Common Variants in Neurodevelopmental Disorders |
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Xin Jin, Scripps Research Institute Massively Parallel Dissection of Gene to Phenotype Relationships using Perturb-seq |
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Thomas Bourgeron †, Institut Pasteur PARIS: Paris Autism Research International Sib-Pair Study |
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Short Talk(s) Chosen from Abstracts
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9:30–9:50 AM |
Coffee Break |
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11:15–12:15 PM |
Meet the Editors |
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12:15–1:00 PM |
Poster Setup |
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12:15–5:00 PM |
On Own for Lunch |
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1:00–10:00 PM |
Poster Viewing |
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2:30–4:30 PM |
Symposia Spotlight 1: Emerging technologies in the study of Neurodevelopmental Disorders |
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Short Talks Chosen from Abstracts
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4:30–5:00 PM |
Coffee Available |
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5:00–7:00 PM |
Genes to Molecular Phenotypes |
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Yukiko Gotoh †, University of Tokyo Genetic and Epigenetic Mechanisms of Cortical Development |
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Willow Coyote-Maestas †, University of California, San Francisco Deep Mutational Scanning Approaches to Correlate Structure and Function of Proteins |
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Sila Ultanir †, Francis Crick Institute Kinase Signaling in Neurodevelopmental Disorders |
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Short Talk(s) Chosen from Abstracts
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7:00–8:00 PM |
Social Hour with Dinner |
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8:00–11:00 AM |
Circuits to Phenotypes |
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Gabrielle Pouchelon †, Cold Spring Harbor Laboratory Interplay between Sensory and Neuromodulatory Inputs and Genetic Programs in Circuit Maturation |
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Guillermina López Bendito †, Instituto de Neurociencias Thalamic Spontaneous Activity in Cortical Sensory Maps Development and Plasticity |
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Botond Roska †, Institute of Molecular and Clinical Ophthalmology (IOB) Basel Asynchrony of Functional Connectivity in Developing Brain of ASD Models |
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Catherine G. Dulac †, Harvard University and HHMI Hypothalamic Regulation of Social Behaviors |
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Short Talk(s) Chosen from Abstracts
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9:00–9:20 AM |
Coffee Break |
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11:00–12:00 PM |
Panel Discussion 1: What to translate? When to translate? How to translate? |
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12:00–1:00 PM |
Poster Setup |
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12:00–5:00 PM |
On Own for Lunch |
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1:00–10:00 PM |
Poster Viewing |
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3:00–4:30 PM |
Career Roundtable |
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4:30–5:00 PM |
Coffee Available |
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5:00–7:00 PM |
Human and Non-Human Models |
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Tomasz Nowakowski, University of California, San Francisco Establishing Tools for Human Neuroscience |
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Pierre Vanderhaeghen †, KU Leuven Interrogating Human Specific and Neurodevelopmental Risk Genes using Chimeric Models |
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Paola Arlotta †, Harvard University Brain Organoids to Study Neurodevelopmental Disorders |
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Short Talk(s) Chosen from Abstracts
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7:00–8:00 PM |
Social Hour with Dinner |
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8:00–11:00 AM |
Environment and Experience |
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Zhaolan (Joe) Zhou, University of Pennsylvania Epigenetic Dissection of Mechanisms underlying Neurodevelopmental Disorders |
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Kristen J. Brennand †, Yale School of Medicine Insights into Gene-Environment Interactions in Neurodevelopmental Disorders |
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Gloria Choi †, Massachusetts Institute of Technology Cytokine Regulation of Brain and Behavior |
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Anca M. Pasca †, Stanford University Neonatal Hypoxia and Pediatric Risk Factors |
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Short Talk(s) Chosen from Abstracts
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9:00–9:20 AM |
Coffee Break |
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11:00–12:00 PM |
Panel Discussion 2: Grand Challenges in NDDs |
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11:00–5:00 PM |
On Own for Lunch |
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2:30–4:30 PM |
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions |
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Short Talks Chosen from Abstracts
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4:30–5:00 PM |
Coffee Available |
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5:00–7:00 PM |
Neurmodulation, Biomarkers, and Therapies |
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Stephan Sanders, University of Oxford Gene Targeting Strategies for Autism and Neurodevelopmental Disorders |
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Allyson Berent †, Foundation for Angelman Syndrome Therapeutics A Roadmap to a Cure: Accelerating Drug Development for Angelman Syndrome |
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Cassiano Carromeu †, Recursion Using Human Pluripotent Stem Cell-Derived Neural Cultures to Assess Safety of New Drugs and Chemicals |
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Short Talk(s) Chosen from Abstracts
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6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
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7:00–8:00 PM |
Social Hour with Dinner |
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8:00–11:00 PM |
Entertainment |
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