4:00–8:00 PM | Arrival and Registration | Courtyard by Marriott Marin Room |
6:00–8:00 PM | Welcome Mixer | Courtyard by Marriott Marin Room |
7:45–8:30 AM | Shuttle to Buck Institute | Courtyard by Marriott Front Desk |
8:00–9:00 AM | Breakfast and Registration | Atrium |
8:30–9:00 AM | Poster Setup | Atrium |
9:00–9:30 AM | Welcome Address from the Organizers | Drexler Auditorium |
Bei B. Zhang, Novo Nordisk NovoNordisk |
Teresa Zimmers, Oregon Health and Science University Knight Cancer Institute Oregon Health and Science University |
9:00–7:00 PM | Poster Viewing | Atrium |
9:30–12:15 PM | Defining Cachexia as a Disease within a Disease | Drexler Auditorium |
* Bette Caan, Kaiser Permanente Session Chair |
* Denis C. Guttridge, Medical University of South Carolina Session Chair |
Vickie Baracos, University of Alberta Clinical Classification of Cancer Cachexia |
Stefan D. Anker, Charité Universitätsmedizin Berlin Cardiac Dysfunction and Wasting at the Heart of Cachexia |
Mariam Jamal-Hanjani, University College London Insights Into Lung Cancer-Associated Cachexia From the TRACERx Study |
Laure Bindels, Université Catholique de Louvain Contribution and Therapeutic Prospects from the Gut Microbiome to Cancer Cachexia |
10:30–10:50 AM | Coffee Break | Atrium |
12:15–1:15 PM | Lunch | Atrium |
1:00–3:00 PM | Poster Session 1 | Atrium |
3:00–3:30 PM | Coffee Available | Atrium |
3:30–5:30 PM | Delineating Underlying Biological Pathways | Drexler Auditorium |
* David J. Glass, Regeneron Pharmaceuticals, Inc. Session Chair |
* Mariam Jamal-Hanjani, University College London Session Chair |
Teresa Zimmers, Oregon Health and Science University Knight Cancer Institute Organ Crosstalk in Cachexia |
Tony Tony Hui, Harvard T.H. Chan School of Public Health Energy Metabolism in Cachexia - Quantitative Fluxomics |
Denis C. Guttridge, Medical University of South Carolina Muscle Microenvironment in Cancer Cachexia |
Andrea Graziani, Università di Torino Short Talk: Short Talk: Impaired cAMP/CREB1 Signaling Drives Mitochondrial Dysfunction in Skeletal Muscle During Cancer Cachexia |
Maria Rohm, Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt Short Talk: Short Talk: Cancer Cachexia Causes Impaired CD8+ T Cell Activation and Lymphopenia that Contributes to Tissue Wasting |
5:30–5:35 PM | Introduction of the Cancer Cachexia Society | Drexler Auditorium |
Andrea Bonetto, University of Colorado Anschutz Medical Campus |
5:35–8:00 PM | On Own for Dinner |
8:00–9:00 PM | Dessert Social Hour with Trivia | Courtyard by Marriott Marin Room |
7:45–8:30 AM | Shuttle to Buck Institute | Courtyard by Marriott Front Desk |
8:00–9:00 AM | Breakfast | Atrium |
8:30–9:00 AM | Poster Setup | Atrium |
9:00–12:00 PM | Cachexia in Chronic Illness | Drexler Auditorium |
* Danna M. Breen, Pfizer Inc. Session Chair |
* Laure Bindels, Université Catholique de Louvain Session Chair |
Marcus D. Goncalves, Weill Cornell Medicine Cachexia and Cancer |
Philip A. Efron, University of Florida Persistent Inflammatory/Immunosuppressive Catabolic Syndrome (PICS) after Sepsis |
David J. Glass, Regeneron Pharmaceuticals, Inc. Cachexia and COVID-19 |
Marilia C Seelaender, University of São Paulo Adipose Tissue Role in Acute COVID-19 and Long COVID Syndrome: A New Form of Cachexia? |
Shinpei Kawaoka, Tohoku University / Kyoto university Short Talk: Short Talk: Systemic Metabolic and Immune Defects in Advanced Cancer Patients Prior to the Onset of Pre-Cachexia |
Aliesha Garrett, Terasaki Institute for Biomedical Innovation Short Talk: Short Talk: Vagal Perturbation of the Liver-Brain Axis Deters Cancer-Associated Cachexia Independent of Tumor Burden |
9:00–7:00 PM | Poster Viewing | Atrium |
10:00–10:20 AM | Coffee Break | Atrium |
12:00–1:00 PM | Lunch | Atrium |
12:30–2:30 PM | Poster Session 2 | Atrium |
2:30–4:30 PM | Workshop | Drexler Auditorium |
* Tony Tony Hui, Harvard T.H. Chan School of Public Health Session Chair |
* Rodney Infante, University of Texas Southwestern Medical School Session Chair |
Houda Cohen, University of Minnesota Chronic Cardiac Wasting-Associated Cardiomyopathy in Post-Tumor-Mediated Cancer Cachexia |
Anja Karlstaedt, Cedars Sinai Medical Center D2-HG Promotes IDH-Mutant Cancer-Associated Autophagic Proteolysis Skeletal Muscle |
Hassan Fakih, UMass Chan Medical School Efficacious and Durable Myostatin Knockdown Using Chemically Optimized siRNAs |
Hong-Wen Tang, Duke-NUS Medical School Deaf1 Regulates Muscle Regeneration through Autophagy |
Muhannad Abu-Remaileh, Dana Farber Cancer Institute Roles of HIF2 and PTHLH in Kidney Cancer-Associated Cachexia: Treatment with a First-In-Class Agent |
Venise Jan Castillon, Memorial Sloan Kettering Cancer Center Systemic Physiological Changes Indicative of Cancer Cachexia at Diagnosis |
Justin L Shahtout, University of Utah Targeting Skeletal Muscle Lipid Hydroperoxides in Cancer Cachexia |
Paige Arneson-Wissink, OHSU PDAC Recovery Associates with Impaired Hepatic metabolism, Delayed Muscle Recovery, and Decreased Activity Levels |
4:30–5:00 PM | Coffee Available | Atrium |
5:00–7:00 PM | Approaches to Therapeutic Intervention | Drexler Auditorium |
* Marcus D. Goncalves, Weill Cornell Medicine Session Chair |
* Vickie Baracos, University of Alberta Session Chair |
Steven Heymsfield, Pennington Biomedical Research Center Digital Technology for Body Weight Phenotyping |
Rodney Infante, University of Texas Southwestern Medical School Harnessing Cachexia Mechanisms to Elucidate Tumor-directed Therapies |
Danna M. Breen, Pfizer Inc. GDF15/Ponsegromab: A Potential Treatment for Cachexia |
Kate Orlowsky, AVEO Oncology Short Talk: Short Talk: A Phase 1b Dose Escalation Study of AV-380 in Combination with Standard of Care Chemotherapy in Metastatic Cancer Patients (pts) with Cachexia and Elevated GDF-15 Levels |
Andrei Turtoi, INSERM Cancer Research Institute of Montpellier, France Short Talk: Short Talk: Nozomitumab: A Potential Treatment for Prevention of Cancer-Induced Cachexia via Reprogramming Macrophage Function in Adipose and Muscle Tissues |
7:00–8:00 PM | On Own for Dinner |
7:45–9:30 PM | Transportation to Novato for Dinner | Courtyard by Marriott Front Desk |