Regenerative Biology of the Female Reproductive System (T3)
April 10-12, 2025  | Wylie Center and Tupper Manor at Endicott College, Beverly, MA, United States
Kara McKinley, Margherita Y Turco, Pradeep Tanwar and Amander Clark
Scholarship Deadline: Feb. 11, 2025 | Abstract Deadline: Mar. 20, 2025 | Early Registration Deadline: Feb. 27, 2025
* Session Chair † Invited but not yet accepted | Program current as of August 23, 2025 8 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Thursday, April 10, 2025
4:00–8:00 PM Registration Conference Center Atrium
6:00–8:00 PM Welcome Mixer with Lite Bites Conference Center Atrium
Friday, April 11, 2025
7:30–8:30 AM Breakfast Beverly Foyer
8:00–8:30 AM Poster Setup Ipswich
8:00–5:00 PM Poster Viewing Ipswich
8:30–9:30 AM Welcome and Keynote Address Beverly Room
  * Kara McKinley, Harvard University
Session Chair
 
  Teresa K. Woodruff, Michigan State University
Remote Presenter - Oncofertility: From Bench to Bedside to Babies
 
9:30–11:30 AM Regenerative Mechanisms in the Female Reproductive Tract Beverly Room
  * Hilary Critchley, University of Edinburgh
Session Chair
 
  Margherita Y Turco, Friedrich Miescher Institute
Unravelling the Mechanisms Underlying Epithelial Repair in the Human Endometrium using Organoids
 
  Kara McKinley, Harvard University
Mechanisms of Post-Menstrual Regeneration in vivo
 
  Pradeep Tanwar, University of Newcastle
Molecular Basis of Fallopian Tube Epithelial Homeostasis
 
10:00–10:20 AM Coffee Break Beverly Foyer
11:30–12:30 PM Lunch Newburyport
12:00–2:30 PM Poster Session 1 Ipswich
2:30–4:30 PM Symposia Spotlight: Short Talks Chosen from Abstracts Beverly Room
  * Andrew Kelleher, University of MIssouri
Session Chair
 
  * Rowan Karvas, University of Colorado- Anschutz Medical Campus
Session Chair
 
  Jason Rizo, University of Missouri-Columbia
Neonatal Uterine Organoids Reveal Insights into Epithelial Specification and Plasticity in Development and Disease.
 
  Elisa Zhang, University of California, Davis
Uterine Injury During Diestrus Leads to Placental and Embryonic Defects in Future Pregnancies in Mice
 
  Katie Leap, Institut Pasteur
Comparative 3D Cell Culture Models of the Mammalian Endometrium to Understand the Evolution of Uterine Function
 
  Dhanvika Reddy Mopure, university of missouri, Columbia
Uncovering Developmental Programs in Endometrial Regeneration Using an Epithelial Ablation Model
 
  Xiaofei Sun, Cincinnati Children's Hospital Research Foundation
Mesenchymal-To-Epithelial Transition of Perivascular Cells Contributes to Endometrial Re-Epithelialization
 
  Bisiayo E Fashemi, Washington University in St Louis
Single-Cell Signatures of High-Grade Serous Ovarian Cancer Patient-Derived Organoids
 
  Hilary Skalski, Michigan State University
Impact of Obesity on the Endometrium
 
  Rachel Thayer, University of California Davis
Developing Insect Experimental Model Systems to Investigate the Female Reproductive Tract
 
4:30–5:00 PM Coffee & Snack Available Beverly Foyer
5:00–7:00 PM Mechanisms Underpinning Fertility and Infertility Beverly Room
  * Alexander Nikitin, Cornell University
Session Chair
 
  Amander Clark, University of California, Los Angeles
Mechanisms of Early Germ Cell Specification and Differentiation
 
  Binyam Mogessie, Yale University
Unraveling the Molecular Origins of Egg Aneuploidies Associated with Female Reproductive Aging
 
  Matteo A. Molè, Stanford University
Modelling Human Embryo Implantation In Vitro Using A Cell-Engineered Receptive Endometrial Scaffold
 
  Patti Murphy, Harvard University
Short Talk: Mechanisms of Uterine Nerve Degeneration During Pregnancy
 
  Benjamin R Barath, University of Debrecen, Faculty of Medicine
Short Talk: Characterizing Human Hofbauer Cells, Trophoblasts, and Their Interactions That Shape the Cellular Architecture and Function of the Fetal-Maternal Interface
 
7:00–8:00 PM Dinner Newburyport
8:00–9:00 PM Trivia Newburyport
Saturday, April 12, 2025
7:30–8:30 AM Breakfast Beverly Foyer
8:00–8:30 AM Poster Setup Ipswich
8:00–5:00 PM Poster Viewing Ipswich
8:30–11:30 AM Dysregulated Regenerative Mechanisms Driving “Benign” Gynecologic Conditions Beverly Room
  * Matteo A. Molè, Stanford University
Session Chair
 
  * Elisa Zhang, University of California, Davis
Session Chair
 
  Linda G. Griffith, Massachusetts Institute of Technology
Identification of Core Pathways Deregulated in Endometriosis using in vitro Avatars
 
  Digna R Velez Edwards, Vanderbilt University Medical Center
Leveraging Clinical Biobanks to Identify Novel Treatments for Uterine Fibroids and Shared Genetic Architecture with Blood Pressure
 
  Hilary Critchley, University of Edinburgh
Failures of “Wound” Repair and Endometrial Function during Abnormal Uterine Bleeding (AUB)
 
  Laura C Bahlmann, Massachusetts Institute of Technology
Short Talk: Old Target, New Tricks: Benchmarking Next Generation c-Jun N-Terminal Kinase (JNK) Inhibitors Using In Vitro Models Toward The Treatment Of Endometriosis
 
  Rowan Karvas, University of Colorado- Anschutz Medical Campus
Short Talk: Blastoids as a Window into Human Trophoblast Development from Pre- to Post-Implantation Stages
 
  Ludivine Doridot, INSERM U1016 - Université Paris Cité
Short Talk: Impact of Endometriosis on Maternal Fetal Interface Development in A Mouse Model
 
  Michal Caspi Tal, Massachusetts Institute of Technology
Short Talk: Lyme Disease Increases Risk for Multiple Gynecological Conditions with Age
 
9:30–9:50 AM Coffee Break Beverly Foyer
9:50–9:55 AM Award Recipient Acknowledgement Beverly Room
11:30–12:30 PM Lunch Newburyport
12:00–2:30 PM Poster Session 2 Ipswich
2:30–3:30 PM Regenerative Biology of the Female Reproductive System: Advances and Applications Beverly Room
  Dineo Khabele, Washington University School of Medicine
Panelist
 
  Amander Clark, University of California, Los Angeles
Panelist
 
  * Linda G. Griffith, Massachusetts Institute of Technology
Panelist
 
3:30–4:00 PM Coffee & Snack Available Beverly Foyer
4:00–6:00 PM Dysregulated Regenerative Mechanisms in Reproductive Cancers Beverly Room
  * Ronald Chandler, Michigan State University
Session Chair
 
  Diego H Castrillon, University of Texas Southwestern Medical Center
Endometrial Cancer Onset and PAX2
 
  Cindrilla Chumduri, Aarhus University
Tissue Homeostasis of the Cervix and its Alterations in Infection and Cancer
 
  Alexander Nikitin, Cornell University
Dysregulated Stem Cells in the Pathogenesis of Gynecological Cancers
 
  Dineo Khabele, Washington University School of Medicine
Drivers of Chemotherapy-Resistant Ovarian Cancer
 
6:00–6:15 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Beverly Foyer
6:15–8:00 PM On Own for Dinner
6:30–10:00 PM Transportation to Dinner Options
Sunday, April 13, 2025
8:00–9:00 AM Departure