Integrative Mitochondrial Medicine (T6)
January 1-4, 2027  | Location to be Determined
Nils-Goran Larsson and Aleksandra Filipovska
* Session Chair † Invited but not yet accepted | Program current as of August 22, 2025 12 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Friday, January 1, 2027
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Saturday, January 2, 2027
7:00–8:00 AM Breakfast
8:00–9:00 AM Welcome and Keynote Address
  Vamsi K. Mootha †, Massachusetts General Hospital
Treating Mitochondrial Dysfunction by Metabolic Interventions
 
9:00–11:15 AM Mitochondrial Genome Editing
  Beverly Y. Mok †, Harvard University
Novel Approaches for Base-Editing of mtDNA
 
  Min Jiang †, Westlake University
Mouse Models with Gene Edited mtDNA Mutations
 
  Carlos T. Moraes †, University of Miami
Repairing Pathogenic mtDNA Mutations with Gene Editing
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:15–12:15 PM Meet the Editors
11:15–1:00 PM Poster Setup
11:15–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1: Hot Topics
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Mitochondrial Synthetic Biology
  Alice Y. Ting †, Stanford University
Chemical Biology Approaches to Probing Molecular Networks in Mitochondria
 
  Martin Fussenegger †, ETH Zürich
Synthetic Biology Approaches to Regulate Metabolism
 
  Aleksandra Filipovska, University of Western Australia
Engineering Mitochondria for Improved Energy Conversion Efficiency
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Sunday, January 3, 2027
7:00–8:00 AM Breakfast
8:00–11:00 AM Mitochondrial Imaging in Disease
  Danielle Grotjahn †, Scripps Research Institute
Regulation of Mitochondrial Dynamics and Disease
 
  Antentor O. Hinton †, Vanderbilt University School of Medicine
FIB-SEM Approaches to Image Mitochondria in the Cell in situ
 
  Gulcin Pekkurnaz †, University of California, San Diego
Mitochondrial Specialization in the Nervous System
 
  Elisa Motori †, University of Cologne
Neuronal Metabolism in Mitochondrial Disease
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–12:00 PM Panel Discussion: Shark Tank Pitch Session for Commercialization
11:00–1:00 PM Poster Setup
11:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
3:00–4:30 PM Career Roundtable
4:30–5:00 PM Coffee Available
5:00–7:00 PM Precision Medicine for Mitochondrial Dysfunction
  Claes Gustafsson †, University of Gothenburg
Treating mtDNA Depletion with Small Molecules
 
  Thomas Keating †, Pretzel Therapeutics
Development of Small Molecules Targeting Mitochondrial Enzymes
 
  Michio Hirano †, Columbia University Medical Center
Treatment of mtDNA Depletion Syndromes with Nucleosides
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Monday, January 4, 2027
7:00–8:00 AM Breakfast
8:00–11:00 AM Metabolic Networks
  Christian Frezza †, University of Cologne
Metabolites Controlling Mitochondrial Function
 
  Nils-Goran Larsson, Karolinska Institutet
The Link between mtDNA Gene Expression and Metabolic Disease
 
  Natalie Niemi †, Washington University in St. Louis
Regulation of Mitochondrial Metabolism
 
  Tomer Shlomi †, Technion
Spatio-Temporal Resolution of Mitochondrial Metabolism
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–5:00 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: New Technologies
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Transplantation of Mitochondria
  Natalie Yivgi-Ohana †, Minovia Therapeutics
Treatment of Pearson´s Syndrome with Mitochondrial Transplantation
 
  Robert McFarland †, University of Newcastle
Preventing Transmission of Mitochondrial Disease by Transfer of Mitochondria to Embryos
 
  Robert Lightowlers †, Newcastle University
A Critical Assessment of What Mitochondrial Transplantation can Achieve
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
7:00–8:00 PM Social Hour with Dinner
8:00–11:00 PM Entertainment
8:00–11:00 PM Cash Bar
Tuesday, January 5, 2027
12:00–11:59 PM Departure