Epigenetics in Health and Disease (T7)
January 1-4, 2027  | Location to be Determined
* Session Chair † Invited but not yet accepted | Program current as of August 27, 2025 6 PM | For the most up-to-date details, visit https://www.keystonesymposia.org
Friday, January 1, 2027
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Saturday, January 2, 2027
7:00–8:00 AM Breakfast
8:00–9:00 AM Welcome and Keynote Address
  Clifford P. Brangwynne †, Princeton University
Phase Separation in Genome Regulation
 
9:00–11:15 AM Genome Architecture in Development and Disease
  Eileen E.M. Furlong †, European Molecular Biology Laboratory
Enhancer-Promoter Interactions in Development
 
  Liling Wan, University of Pennsylvania
Condensates in Genome Organization
 
  Anders Sejr Hansen †, Massachusetts Institute of Technology
High-Resolution 3D Genome Imaging
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:15–1:00 PM Poster Setup
11:15–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1: Epigenetic Mechanisms Governing Cell Fate in Health and Disease
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Epigenetic Dysregulation in Cancer: Mechanisms and Therapeutic Targets
  Margaret A Goodell †, Baylor College of Medicine
DNA Methylation in Hematological Malignancies
 
  Ali Shilatifard †, Northwestern University
Transcriptional Elongation in Health and Disease
 
  Pamela Ting †, Novartis Institutes for BioMedical Research
A Molecular Glue Degrader of the WIZ Transcription Factor for Fetal Hemoglobin Induction
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Sunday, January 3, 2027
7:00–8:00 AM Breakfast
8:00–11:00 AM Epigenetic Mechanisms of Transcriptional Control
  Karen Adelman †, Harvard Medical School
Transcriptional Elongation and Enhancer-Promoter Communication
 
  Kathrin Plath †, University of California, Los Angeles
RNA-Mediated Regulation of Gene Expression
 
  Geneviève Almouzni †, Centre National de la Recherche Scientifique
Histone Variants in Chromatin Assembly and Genome Stability
 
  Bradley E. Bernstein, Dana-Farber Cancer Institute
Functional Epigenomics and Cancer Mechanisms
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–1:00 PM Poster Setup
11:00–5:00 PM On Own for Lunch
1:00–3:00 PM Symposia Spotlight 2: Environmental Inputs and Chromatin Dynamics in Physiology and Disease
  Short Talks Chosen from Abstracts
 
1:00–10:00 PM Poster Viewing
3:00–4:30 PM Career Roundtable
4:30–5:00 PM Coffee Available
5:00–7:00 PM Mapping and Perturbing the Epigenome
  Bing Ren †, Ludwig Institute for Cancer Research
3D Genome and Epigenomic Architecture
 
  Charles Gersbach †, Duke University
CRISPR-Based Epigenome Editing
 
  Alla Sigova †, CAMP4 Therapeutics
RNA Amplifier Therapeutics Targeting Regulatory RNAs to Upregulate Disease-Associated Genes
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Monday, January 4, 2027
7:00–8:00 AM Breakfast
8:00–11:00 AM Epigenetic Modification Dynamics and Function in Development and Disease
  Shelley L Berger †, University of Pennsylvania
Histone Modifications in Gene Regulation
 
  Wei Xie †, Tsinghua University
Epigenetic Regulation in Early Development
 
  Asifa Akhtar †, Max Planck Institute of Immunobiology and Epigenetics
Dosage Compensation in Development
 
  Kristian Helin †, The Institute of Cancer Research
Histone Modifying Enzymes Regulators in Cancer
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–5:00 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 3: Emerging Tools, Technologies, and Therapeutics
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions
5:00–7:00 PM Epigenetic Plasticity in Physiology and Tissue Homeostasis
  Susan M Kaech †, The Salk Institute
Metabolism, Histone Modifications, and Immunity
 
  Justin Brumbaugh †, University of Colorado
Epigenetic Regulation in Cell Plasticity and Regeneration in the Intestinal Epithelium
 
  Jan Zylicz †, University of Copenhagen
Epigenetic and Metabolic Regulation of Early Development
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
8:00–11:00 PM Entertainment
8:00–11:00 PM Cash Bar
Tuesday, January 5, 2027
12:00–11:59 PM Departure