Fibrosis: Targeting Mechanisms of Repair, Progression, and Resolution (V8)
January 1-5, 2028
| Location to be Determined
Boris Hinz, Daniel Tschumperlin and Anna Zagorska
Saturday, January 1, 2028
| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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| 8:00–8:10 AM |
Welcome Remarks (Joint) |
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| 8:10–9:00 AM |
Keynote Address (Joint) |
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Shannon J Turley †, Amgen Inc.
Cell Heterogeneity in Immunity and Fibrosis |
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| 9:00–11:15 AM |
Intercellular Crosstalk in the Fibrotic Niche (Joint) |
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Edward E. Morrisey †, University of Pennsylvania
Mesenchymal-Epithelial Cell Niches Coordinate Regenerative Responses in the Lung |
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Matthew Buechler †, University of Toronto
Fibroblast-Macrophage Crosstalk in Skin and Lung Fibrosis |
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Fiona M. Powrie †, University of Oxford
Immune and Stromal Micro-Niches Shape Treg Function |
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Short Talk(s) Chosen from Abstracts
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|
| 9:30–9:50 AM |
Coffee Break |
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| 11:15–1:00 PM |
Poster Setup |
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| 11:15–5:00 PM |
On Own for Lunch |
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| 11:25–12:25 PM |
Meet-the-Editors (Joint) |
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| 1:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Symposia Spotlight 1: Antifibrotic Drug Development: What Have We Learned? |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Cross-Organ Fibrosis Biology and Therapeutics |
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Andrea Sáez †, Agomab Therapeutics
Safer Approaches to Target TGF-β1 Pathways |
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Robert F. Schwabe †, Columbia University
Hepatic Stellate Cells Balance Liver Homeostasis, Protection, and Fibrogenesis |
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Kevin Hart †, Pfizer
Fibrosis and Immunity |
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Short Talk(s) Chosen from Abstracts
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|
| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Manifestation of Fibrosis: Matrix, Memory, and Mechanics |
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Sara Wickström †, Max Planck Institute for Molecular Biomedicine
Epigenetic and Mechanical Regulation of Fibrotic Cell Programs |
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Daniel Tschumperlin, Mayo Clinic
Mediators of Fibrotic Activation and Epigenetic Memory in Lung Fibroblasts |
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Alexandra Naba †, University of Illinois Chicago
The Matrix Proteome: Lessons Learned from the Tumor Stroma |
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Thomas Barker †, University of Virginia
Matrix Mechanosensing in Repair and Fibrosis |
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Short Talk(s) Chosen from Abstracts
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|
| 9:00–9:20 AM |
Coffee Break |
|
| 11:00–1:00 PM |
Poster Setup |
|
| 11:00–5:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
|
| 1:30–3:00 PM |
Career Roundtable (Joint) |
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| 3:30–4:30 PM |
Panel Discussion 1: What’s in a Name – How do we Align Stromal Cell Nomenclature? |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Underappreciated Organs and Players |
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Erica Herzog †, Yale University School of Medicine
A Nerve-Fibroblast Axis in Mammalian Lung Fibrosis |
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Tanya Shaw †, King’s College London
Are Keloids Fibrotic? |
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Giovanni Ligresti †, Boston University
Activated Endothelial Cell States Persist in Progressive Lung Fibrosis |
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Short Talk(s) Chosen from Abstracts
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|
| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Reversing Fibrosis: Regeneration, Resolution, and Reprogramming |
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Jennifer Y. Chen †, University of California, San Francisco
Resolving Fibrosis by Stimulating HSC-Dependent Extracellular Matrix Degradation |
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Elizabeth F. Redente †, National Jewish Health
Fibroblasts Enrich Specific Signaling Pathways during Lung Fibrosis Resolution |
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Prakash Ramachandran †, University of Edinburgh
The Role of Inflammation in Liver Fibrosis Resolution |
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Anna Zagorska, Gilead Sciences Inc.
True North: What Will It Take to Reverse Fibrosis in the Clinic? |
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Short Talk(s) Chosen from Abstracts
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|
| 9:00–9:20 AM |
Coffee Break |
|
| 11:00–12:00 PM |
Panel Discussion 2: How is Fibrosis Measured, Quantified, and Defined Molecularly and Clinically? |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 2:30–4:30 PM |
Symposia Spotlight 2: Pre-Pre-Clinical: Experimental Systems to Study Fibrosis |
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Short Talks Chosen from Abstracts
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|
| 4:30–5:00 PM |
Coffee Available |
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| 5:00–6:45 PM |
Targeting the Stroma: Cell Therapies, Immunotherapies, and Delivery Systems (Joint) |
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Michael B. Brenner †, Harvard Medical School
T Regulatory Cell States in Human Tissues in Autoimmune Arthritic Diseases |
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Cedric Hubeau †, AbbVie
Anti-Fibrotic Drug Development |
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Boris Hinz, St. Michael's Hospital and University of Toronto
Stromal Cell Therapies to Heal (Rat) Fibrosis: Nudging the Immune System |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 PM |
Entertainment |
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Wednesday, January 5, 2028
