Targeted Delivery of Nucleic Acid Medicines (X1)
January 1-4, 2027
| Location to be Determined
C. Frank Bennett, Beverly L. Davidson and Daniel G. Anderson
| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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Saturday, January 2, 2027
| 8:00–9:00 AM |
Welcome and Keynote Address (Joint) |
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Eric N. Olson †, University of Texas Southwestern Medical Center
Single-AAV base Editing Therapies for Duchenne Muscular Dystrophy |
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| 9:00–11:15 AM |
Viral Delivery of Genome Editors and Genetic Medicines (Joint) |
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Beverly L. Davidson, Children’s Hospital of Philadelphia and University of Pennsylvania
AAV Capsid Engineering for Broad CNS Distribution |
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Sonia Vallabh †, Broad Institute
Development of Medicines to Treat Prion Diseases: A Personal Journey |
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Charles Gersbach †, Duke University
AAV-Delivered Epigenome Editors |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
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| 11:15–1:00 PM |
Poster Setup |
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| 11:15–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions |
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| |
Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Tissue Targeting of LNPs |
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Daniel G. Anderson, Massachusetts Institute of Technology
LNP Delivery of Nucleic Acid Medicines |
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Jessica A. Couch †, ReCode Therapeutics
LNP Delivery with the CNS |
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Kathryn Whitehead †, Carnegie Mellon University
Optimizing LNPs Delivery Vehicles |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–9:00 AM |
Keynote Address (Joint) |
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| |
David R. Liu †, Broad Institute, HHMI, and Harvard University
Development and Application of Virus-Like Particles for Genome Editing in vivo |
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| 9:00–9:20 AM |
Coffee Break |
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| 9:00–11:00 AM |
In vivo Genome Editing via Non-Viral Delivery (Joint) |
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Birgit C. Schultes †, IntelliaTherapeutics Inc.
Clinical Results from Liver Genome Editing in vivo |
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Rebecca Ahrens-Nicklas †, Children's Hospital of Philadelphia
Personalized Therapeutic Genome Editing for Hepatic Inborn Errors of Metabolism |
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Leah R. Sabin †, Regeneron Pharmaceuticals
Novel Delivery Strategies for Genetic Medicines |
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Short Talk(s) Chosen from Abstracts
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|
| 11:00–1:00 PM |
Poster Setup |
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| 11:00–5:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
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| 3:00–4:30 PM |
Career Roundtable |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Ligand Mediated Delivery of Nucleic Acid Medicines |
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Deborah Law †, Xaira Therapeutics
Machine Learning Design of Ligands for Targeted Delivery of Nucleic Acid Medicines |
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Vadim Dudkin †, Souffle Therapeutics
Targeted Delivery of Genetic Medicines |
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C. Frank Bennett, Ionis Pharmaceuticals, Inc.
Targeted Delivery of Oligonucleotide Drugs |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Translation of Genetic Medicines to the Clinic |
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Joseph B. Bolen †, Orna Therapeutics
Tissue Selective Delivery of Circular RNAs |
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Christian Mueller †, Sanofi
Genome Editing in vivo via Non-Viral Delivery Platforms |
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Dirk Grimm †, University of Heidelberg
AAV Capsid Engineering |
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Nicole K. Paulk †, UCSF
AAV Delivery to Cancer Cells |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 2:30–4:30 PM |
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions |
|
| |
Short Talks Chosen from Abstracts
|
|
| 4:30–5:00 PM |
Coffee Available |
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| 5:00–6:45 PM |
New Delivery Technologies |
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Dong-Jiunn Jeffery Truong †, Helmholtz Munich
VLP Deliver of cas Enzymes |
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Akin Akinc †, Alnylam Pharmaceuticals Inc.
Use of Endogenous Retroviral Capsid for Delivery of Nucleic Acid Medicines |
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Bowen Li †, University of Toronto
Machine Learning Design of LNP Delivery Systems |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 PM |
Entertainment |
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