Microbiome Metabolism and Metabolites: Discovery, Mechanism, and Function (X2)
January 31-February 3, 2028 | Fairmont Monte Carlo, Monte Carlo, Monaco
Sloan Devlin and Kenya Honda
* Session Chair † Invited but not yet accepted | Program current as of October 6, 2026 8 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, January 31, 2028
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Tuesday, February 1, 2028
7:30–8:30 AM Breakfast
8:00–8:30 AM Poster Setup
8:15–5:00 PM Poster Viewing
8:30–8:40 AM Welcome Remarks
8:40–10:00 AM Keynote Session (Joint)
  Wendy S Garrett †, Harvard School of Public Health
Microbial Metabolites at the Interface of Mucosal Immunity, Inflammation, and Cancer
 
  Eran Elinav †, Weizmann Institute of Science
Metagenome-informed Metaproteomics Signatures of Human Health
 
10:00–10:20 AM Coffee Break
10:00–11:45 AM Decoding Microbiome-Host Interactions: From Data Signatures to Molecular Mechanisms (Joint)
  Christoph A. Thaiss †, Arc Institute & Stanford University
Intestinal Interoception Links the Aging Microbiome to Cognitive Decline
 
  Lora V. Hooper †, University of Texas Southwestern Medical Center
Microbiota Control of Intestinal Epithelial and Immune Physiology
 
  Short Talk(s) Chosen from Abstracts
 
11:55–12:55 PM Meet-the-Editors (Joint)
12:55–1:55 PM Lunch
1:00–2:30 PM Posters
2:30–4:30 PM Symposia Spotlight 1: New Approaches to Microbiome Metabolite Discovery.
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Metabolites, Genes, and Enzymatic Logic of the Microbiome
  Pierre Stallforth †, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute
Natural Product Discovery from Ancient Human Microbiomes
 
  Pieter Dorrestein †, University of California, San Diego
Connecting Microbiome Metabolomics to Molecular Structures and Functions
 
  Emily P Balskus †, HHMI-Harvard University
Deciphering Human Gut Microbial Metabolism with Chemistry
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM On Own for Dinner
Wednesday, February 2, 2028
7:30–8:30 AM Breakfast
8:00–8:30 AM Poster Setup
8:15–5:00 PM Poster Viewing
8:30–11:30 AM Metabolic Cooperation and Competition in Microbial Communities
  Jeremiah Faith †, Icahn School of Medicine at Mount Sinai
From Defined Microbial Communities to Live Biotherapeutics
 
  Samuel Light †, University of Chicago
Metabolic Strategies that Shape Gut Microbial Community Function
 
  Alvaro Sanchez †, Institute of Functional Biology & Genomics, CSIC
Predictive Rules for Microbial Community Assembly and Metabolic Interactions
 
  Lindsay R Kalan †, McMaster University
Chemical Ecology and Competitive Interactions in the Skin Microbiome
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:30–12:30 PM Lunch
12:30–2:30 PM Posters
3:00–4:30 PM Career Roundtable
4:30–5:00 PM Coffee Available
5:00–7:00 PM Nutrition, Host Metabolism, and Microbial Chemistry
  Peter J Turnbaugh †, University of California, San Francisco
Mechanisms Linking Diet to the Gut Microbiome and Host Metabolism
 
  Elizabeth Sattely †, Stanford University
Gut Microbial Metabolism of Specialized Compounds from Dietary Plants
 
  Weston Whitaker †, Pennsylvania State University
Engineering a Metabolic Niche for Controlled Gut Colonization
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM On Own for Dinner
Thursday, February 3, 2028
7:30–8:30 AM Breakfast
8:30–11:30 AM Microbial Molecules as Signals Across Host Systems
  Sloan Devlin, Harvard Medical School
Gut Microbial Chemistry of Host-Derived Compounds
 
  Mohamed S Donia, Princeton University
Microbiome Biosynthetic Gene Clusters as Sources of Host-Active Molecules
 
  Andreas J. Bäumler †, University of California, Davis
Host-Derived Metabolites as Drivers of Microbial Signaling and Systemic Disease
 
  Lisa Maier †, University of Tübingen
Genes and Mechanisms Underlying Drug-Microbiome-Host Interactions
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:40–12:40 PM Panel Discussion: Direct Translation of the Microbiome: Industry Perspectives (Joint)
12:40–1:40 PM Lunch
2:30–4:30 PM Symposia Spotlight 2
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM From Host Phenotypes to Causal Microbial Molecules
  Kenya Honda, Keio University School of Medicine
Human Microbiota to Causal Immunomodulatory Bacteria and Metabolites
 
  Pamela Chang †, Cornell University
Chemical Probes and Microbial Metabolites Linking the Gut Microbiome to Inflammation and Host Defense
 
  Ara Koh †, POSTECH
Gut Microbial Metabolites in Neurologic and Metabolic Disease
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions
7:00–8:00 PM On Own for Dinner
Friday, February 4, 2028
12:00–11:59 PM Departure