Computational Drug Discovery: Tools Across the Translational Pipeline (X3)
January 1-4, 2027
| Location to be Determined
Aicha BenTaieb and Jakob Kather
| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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Saturday, January 2, 2027
| 8:00–9:00 AM |
Welcome and Keynote Address (Joint) |
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James Zou †, Stanford University
Talk Title to be Announced |
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| 9:00–11:15 AM |
Decoding Biology to Build Target Hypotheses |
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Debora Marks †, Harvard Medical School
Generative Approaches to Uncover Gene-Gene Dependencies |
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David R. Kelley †, Calico Life Sciences
Predicting Gene Regulation across Tissues |
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Sara Mostafavi †, Genentech
Sequence to Function Models and Agents for Target Discovery |
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Iya G. Khalil †, GNS Healthcare
Foundation Models for Biology and their Impact on Target Discovery |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
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| 11:15–12:15 PM |
Panel Discussion 1: From Perturbation to Validation - How do we Define Confidence in New Targets? |
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| 12:15–1:00 PM |
Poster Setup |
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| 12:15–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Modeling Perturbations to Validate Targets |
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Ryan Fukushima †, Tempus
The Role of Real-World Data and Tumor Organoids for Target Validation |
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Patrick Schwab †, GSK
Machine Learning for Causal Biology |
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Mingyao Li †, University of Pennsylvania School of Medicine
Spatial Biology for Biomarker and Target Discovery |
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Shekoofeh Azizi †, Google DeepMind
How do we Validate Agentic LLMs for Therapeutics? |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Drug Design and Preclinical Development: Simulating Therapeutics and Translation (Joint) |
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Dean Ho †, National University of Singapore
Simulating First in Human Dosing Studies in Oncology |
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Regina Barzilay †, Massachusetts Institute of Technology
ML for Drug Discovery and Oncology Success Stories |
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Philip Kim †, University of Toronto
Talk Title to be Announced |
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Cesar de la Fuente †, University of Pennsylvania
Talk Title to be Announced |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–12:00 PM |
Panel Discussion 2: The Future of Antibody and Drug Design –Subject Matter Experts, Automation and Robotics, or AI? (Joint) |
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| 11:00–1:00 PM |
Poster Setup |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 1:45–2:45 PM |
Panel Discussion 3: Can AI-Driven Simulations Replace or Refine Preclinical Studies? |
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| 3:00–4:30 PM |
Career Roundtable |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Modeling Efficacy and Safety Before the First Dose |
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Mohamed Shahin †, Pfizer
Modeling and Simulations Meet AI for Clinical Pharmacology |
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Caroline Chung †, University of Texas MD Anderson Cancer Center
How to Unlock EHRs for Real-World Evidence |
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Jorge S. Reis-Filho †, AstraZeneca
Agentization of Pharma R&D in 2030 - Where are we Headed |
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Short Talk(s) Chosen from Abstracts
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| 8:00–10:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Where are we with Multimodal Learning from Clinical and Real-World Data? |
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Faisal Mahmood †, Brigham and Women's Hospital
Autonomous Research Agents and Multimodal Foundation Models |
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Leonor Cerda-Alberich †, La Fe Health Research Institute
Learning from Real World Data in Oncology |
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Marinka Zitnik †, Harvard Medical School
Multi-Agent Systems for Learning from Clinical Data |
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Maria Alice Franzoi †, Gustave Roussy
Learning from Real-World Data at Scale |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–12:00 PM |
Panel Discussion 4: Human/Machine Interactions, how do we Leverage Agentic AI in Multidisciplinary Teams? |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 2:30–4:30 PM |
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–6:45 PM |
Integration and Iteration: Future of AI-driven R&D |
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Ariel Dora Stern †, University of Potsdam
Regulatory Barriers for Real-World Translation of Digital Technologies |
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Magdalena Wekenborg †, TU Dresden
Human-Machine Interaction in Scientific Agent Teams |
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Arsela Prelaj †, Istituto Nazionale Tumori di Milano
Training the Next Generation of Biomedical Researchers in the AI Age |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 PM |
Entertainment |
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