Neural-Immune Interactions: Immune Modulation of CNS Biology (X6)
April 11-14, 2027  | Whistler Conference Centre, Whistler, BC, Canada
Dimitry Ofengeim, Martin Kerschensteiner and Soyon Hong
* Session Chair † Invited but not yet accepted | Program current as of September 25, 2025 5 PM | For the most up-to-date details, visit https://www.keystonesymposia.org
Friday, January 1, 2027
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Saturday, January 2, 2027
7:00–8:00 AM Breakfast
8:00–9:30 AM Welcome and Keynote Session (Joint)
  Alfred Njamnshi †, University of Yaoundé
Infectious Disease Life-Time Impact on Cognition
 
  Daniel S. Reich †, NINDS, National Institutes of Health
Combining Advanced Imaging and Biological Insights for Better Disease Progression
 
9:30–9:50 AM Coffee Break
9:30–11:15 AM Molecular Insights into the Interplay between Neurodegeneration and Neuroinflammation (Joint)
  Li Gan †, Weill Cornell Medicine
Converging Molecular Mechanisms of Neurodegeneration
 
  Mariko Bennett †, University of Pennsylvania
The Potential of Microglia-Based Therapies in Neurodegeneration
 
  David M Holtzman †, Washington University
Innate and Adaptive Immune System in tau-Mediated Neurodegeneration
 
  Short Talk(s) Chosen from Abstracts
 
11:15–1:00 PM Poster Setup
11:15–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Glial and Innate Drivers of CNS Inflammation
  Brad Zuchero †, Stanford University
Oligodendrocytes Plasticity and Immune Drivers
 
  Soyon Hong, University College London
Microglia-Synapse Biology in Brain Homeostasis and Pathology
 
  Martin Kerschensteiner, Ludwig Maximilians University Munich
Myeloid Cell Actions and Interactions in the Inflamed CNS
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Sunday, January 3, 2027
7:00–8:00 AM Breakfast
8:00–11:00 AM The Role of the Adaptive Immune System Beyond Autoimmunity
  Menna R Clatworthy †, University of Cambridge
Immune Cells in Border Tissues Protect the CNS from Infection and Contribute to CNS Diseases
 
  Arthur Liesz †, Ludwig-Maximilians-Universität München
Deleterious and Beneficial Roles of the Adaptive Immune System following Brain Ischemia
 
  Doron Merkler †, University of Geneva
Role of Tissue Resident T cells in CNS Infection and Immunity
 
  Dimitry Ofengeim, Sanofi
Interplay of the Innate and Adaptive Immune System in Neurodegeneration
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–1:00 PM Poster Setup
11:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
3:00–4:30 PM Career Roundtable
4:30–5:00 PM Coffee Available
5:00–7:00 PM Emerging Concepts of Neuro-Immune Communication
  Michael T. Heneka †, University of Luxembourg
Structural and Molecular Bridges between Neurons and Microglia
 
  Gloria Choi †, Massachusetts Institute of Technology
Cytokines as Modulators of Neuronal Activity and Development
 
  Isaac Chiu †, Harvard Medical School
Neuronal Pathogen Sensing Mechanism in Neuroinflammation and Neurodegeneration
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Monday, January 4, 2027
7:00–8:00 AM Breakfast
8:00–11:00 AM Translating Innovation: Clinical Advances in Neurodegeneration and Neuroimmunology (Joint)
  Henrik Zetterberg †, University of Gothenburg
Biomarkers in Neurodegeneration and Neuroinflammation
 
  Maura Malpetti †, University of Cambridge
Advances in PET Neuroimaging Across Neurodegeneration and Neuroinflammation
 
  James Keaney †, F. Hoffmann-La Roche
Omics Approaches to Drug Discovery in Neurodegeneration and Neuroinflammation
 
  Joy Yu Zuchero †, Denali Therapeutics Inc
Challenges for CNS Drug-Discovery
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–5:00 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM Regulation of Immune Responses across Compartments
  Andrew Yang †, University of California, San Francisco
Decoding Immune and Protein Crosstalk between the Brain and Body
 
  Rejane Rua †, CIML
Exploring the Functions of the Immune Sentinels at the Brain Borders to Control Neuroinflammation
 
  Maria Lehtinen †, Harvard Medical School
The Choroid Plexus: A Command Center for Brain-Body Communication during Inflammation
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
7:00–8:00 PM Social Hour with Dinner
8:00–11:00 PM Cash Bar
8:00–11:00 PM Entertainment
Tuesday, January 5, 2027
12:00–11:59 PM Departure