Regulation of Barrier Immunity (X8)
February 18-21, 2024  | Fairmont Banff Springs, Banff, AB, Canada
David Artis, Yasmine Belkaid, Fiona M. Powrie and Kenya Honda
Scholarship Deadline: Nov. 10, 2023 | Abstract Deadline: Nov. 10, 2023 | Early Registration Deadline: Dec. 15, 2023
* Session Chair † Invited but not yet accepted | Program current as of August 23, 2025 8 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Sunday, February 18, 2024
4:00–8:00 PM Arrival and Registration Van Horne Foyer
6:00–8:00 PM Welcome Mixer Van Horne Foyer
Monday, February 19, 2024
7:00–8:00 AM Breakfast President's Hall
8:00–9:30 AM Welcome and Keynote Session Van Horne B
  Hamida Hammad, Ghent University & VIB
Regulation of Barrier Immunity in the Lung
 
  Kathy D. McCoy, University of Calgary
Microbial Regulation of Stomal-immune Cross-talk in the Gut
 
9:30–9:50 AM Coffee Break Van Horne Foyer
9:30–11:15 AM Host-Microbe Interactions in Health and Disease Van Horne B
  Kenya Honda, Keio University School of Medicine
Exploring and Harnessing the Microbiota for Disease Prevention and Therapy
 
  Michael A. Fischbach, Stanford University
Dietary-Derived Metabolites Regulate Inflammation at Barriers
 
  Eran Elinav, Weizmann Institute of Science
Microbiota Metabolite Regulation of Immune Function
 
  Michael G. Constantinides, Scripps Research
Short Talk: Short Talk: Antibiotic Use in Early Life Impairs MAIT Cell-mediated Immunity
 
  Rebecca Jeffery, University of Oxford
Short Talk: Short Talk: Delineating the Causal Role of the Gut Microbiota in Experimental Colitis
 
11:15–1:00 PM Poster Setup Van Horne C
11:15–5:00 PM On Own for Lunch
1:00–2:00 PM Career Roundtable (Joint)
  Amariliz Rivera-Medina, Rutgers New Jersey Medical School
Associate Professor
 
  David Blehert, USGS
Chief of the National Wildlife Health Center's Laboratory Sciences Branch
 
  John Robert Grainger, University of Manchester
Principal Investigator
 
  Jamie M. Orengo, Regeneron Pharmaceuticals Inc.
Vice President Research, Allergy and Immunity
 
  Jillian Astarita, TRex Bio
Principal Scientist
 
1:00–10:00 PM Poster Viewing Van Horne C
2:30–4:30 PM Workshop 1: Emerging Topics in Barrier Immunity Van Horne B
  Hiutung Chu, UC San Diego
A Bacterial Sialidase Mediates Early Life Colonization by a Pioneering Gut Commensal
 
  Oliver J. Harrison, Benaroya Research Institute
Antigen-Level Resolution of Commensal-Specific B Cell Responses Enabled by Phage-Display Screening and B cell Tetramers
 
  Upasana Das Adhikari, Massachusetts General Hospital/ Harvard med School
Role of Immunometabolic Dysregulation of Intestinal CD8+ T Cells in the Disruption of Intestinal Barrier Integrity in People with HIV
 
  Katherine Nico, Stanford University
CD8+ T Cell Depletion by Commensal Type 2 Immune Stimuli
 
  Carla Hernández-Cabanyero, University of Lausanne
Deciphering Streptococcus salivarius’s Impact On Small Intestinal Inflammation In Stunted Children
 
  Smita Gopinath, Harvard School of Public Health
Vaginal Lactobacilli Produce Broadly Anti-inflammatory Small Molecule Effectors
 
4:30–5:00 PM Coffee Available Van Horne Foyer
5:00–7:00 PM Vascular-Epithelial-Immune Interactions at Barrier Surfaces Van Horne B
  Yasmine Belkaid, Pasteur Institut
Dietary Regulation of Inflammation
 
  Jakob H. von Moltke, University of Washington
Tuft Cell Sensing of the Barrier Surface
 
  Maria Rescigno, Humanitas University
The Microbiota in Gut-Liver- Brain Axis
 
  Jamie M. Orengo, Regeneron Pharmaceuticals Inc.
Cytokines in Asthma
 
7:00–8:00 PM Social Hour with Lite Bites President's Hall
7:30–10:00 PM Poster Session 1 Van Horne C
Tuesday, February 20, 2024
7:00–8:00 AM Breakfast President's Hall
8:00–11:00 AM Neuro-Immune Regulation of Barrier Immunity Van Horne B
  Brian Kim, Mount Sinai
Remote Presentation: Neuronal Regulation of Skin Barrier Function
 
  Daniel Mucida, Rockefeller University
Circadian Control of Duodenal Regulatory T Cells by Enteric Neurons and Eosinophils
 
  David Artis, Weill Cornell Medical College
Neuro-Immune Interactions in Tissue Homeostasis
 
  Wen Zhang, Weill Cornell Medicine
Short Talk: Short Talk: Nociceptor Regulation of Intestinal Inflammation and Tissue Protection
 
  Ari B. Molofsky, University of California, San Francisco
Short Talk: Short Talk: Distinct Early and Late Programs of Fibroblast - immune Crosstalk Govern Functional Responses to Brain Injury
 
9:00–9:20 AM Coffee Break Van Horne Foyer
11:00–1:00 PM Poster Setup Van Horne C
11:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Van Horne C
2:30–4:30 PM Workshop 2: Emerging Topics in Barrier Immunity Van Horne B
  Nichole A. Broderick, Johns Hopkins University
A Drosophila Model for Infection-induced Loss of Intestinal Barrier Function and Homeostasis
 
  Adam Lacy-Hulbert, Benaroya Research Institute
Disruption of Integrin avß6 in Intestinal Epithelial Cells Predisposes to Ulcerative Colitis
 
  Walter Mowel, Yale University
Dissecting Epigenetic and Cellular Determinants of Trained Immunity
 
  Takato Kusakabe, Weill Cornell Medicine
Gut Fungi Amplify Inflammation, Causing Lasting Impact on Immune Response in Severe COVID-19
 
  Wenqing Zhou, Weill Cornell Medicine
ILC3s Sense Gut Microbiota through STING to Initiate Immune Tolerance
 
  Emily E. Thornton †, University of Oxford
Immune Microniches Shape Intestinal Treg Function
 
  Catherine Lozupone, University of Colorado AMC
Immunologic Alterations in the Colonic Mucosa and Blood of HIV Positive and Negative Men who have Sex with Men is Associated with Gut Microbiome and Sexual Behaviors
 
4:30–5:00 PM Coffee Available Van Horne Foyer
5:00–7:00 PM Dietary Regulation of Microbiota and Metabolites at Barrier Surfaces Van Horne B
  Shruti Naik, New York University Langone Health
Regulation of Sensing and Inflammation in the Skin
 
  Lora V. Hooper, University of Texas Southwestern Medical Center
Bacterial Regulation of Epithelial Barriers
 
  John Robert Grainger, University of Manchester
Type I IFN-induced IFN-gamma Instructs Monocyte-mediated Systemic Bacterial Protection during Type 2 Mucosal Infection
 
  Emily M. Eshleman, Cincinnati Children's Hospital Medical Center
Short Talk: Short Talk: Microbiota Epigenetically Direct Tuft Cell Differentiation to Control Type 2 Immunity
 
  Mohammad Arifuzzaman, Weill Cornell Medicine
Short Talk: Short Talk: Approaching Precision Nutrition: Dietary Fiber and Microbiota-derived Bile Acids Regulate Intestinal Type 2 Inflammation
 
7:00–8:00 PM Social Hour with Lite Bites President's Hall
7:30–10:00 PM Poster Session 2 Van Horne C
Wednesday, February 21, 2024
7:00–8:00 AM Breakfast President's Hall
8:00–11:00 AM Initiation and Regulation of Chronic Inflammation and Cancer Van Horne B
  Fiona M. Powrie, University of Oxford
Regulation of Inflammation
 
  Feng Shao, National Institute of Biological Sciences
Molecular Mechanisms of Bacterial Infection and Host Innate Immunity Defense
 
  Mark A. Travis, University of Manchester
Regulation of Barrier Immunity by Integrins and TGF-beta
 
  Kristen Kay, Cleveland Clinic
Short Talk: Short Talk: Spermidine Promotes a Pro-tumorigenic Immune Environment via CD8+ T Cell Inhibition in Glioblastoma
 
  Silvia Pires, Weill cornell medicine
Short Talk: Short Talk: TL1A Drives ILC-mediated Granulopoiesis and Colitis Associated Cancer
 
9:00–9:20 AM Coffee Break Van Horne Foyer
11:00–5:00 PM On Own for Lunch
2:30–4:30 PM Workshop 3: Emerging Topics in Barrier Immunity Van Horne B
  Libby Jennings, University of Oxford
An Extracellular Matrix Gene Signature Expressed by Cells the IBD Ulcer Niche is Associated with Treatment Non-responsive Disease
 
  Wei Yang, Weill Cornell Medicine
Bhlhe40 in Group 3 Innate Lymphoid Cells Shapes TL1A-Dependent Commensal T Cell Immunity
 
  Laura Markey, Massachusetts Institute of Technology
Commensal Skin Bacteria Exacerbate Inflammation and Delay Skin Healing
 
  Kellen Cavagnero, UCSD
CXCL12+ Dermal Adipocyte Lineage Fibroblast Subsets Drive Neutrophil Recruitment and Host Defense through Recognition of IL-17 and TNF
 
  Nicolas Bouladoux, NIH / NIAID
Deciphering the Crosstalk between Skin Commensals and the Immune System
 
  Jaechul Lim, Seoul National University
Induction of Natural IgE by Glucocorticoids and Regulation of Gut Homeostasis
 
  Graham Britton, Icahn School of Medicine at Mount Sinai
Microbiomes from Humans with Diverse Immune-mediated Diseases Share Inflammatory Properties that Affect Intestinal and Peripheral Tissues
 
4:30–5:00 PM Coffee Available Van Horne Foyer
5:00–6:45 PM Cross-Tissue Interactions: Gut-Brain, Lung-Brain and Beyond Van Horne B
  Anna Victoria Molofsky, University of California, San Francisco
Neuronal Control of Inflammation in the CNS
 
  Carla V. Rothlin, Yale University
Integration of Recognition of Cell Death Recognition and Environmental Signals
 
  Roham Parsa, The Rockefeller University
Short Talk: Short Talk: Distinct Clonal Distribution of CD4+ T Cells during Viral Infections
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Van Horne B
7:00–8:00 PM Social Hour with Lite Bites President's Hall
8:00–11:00 PM Entertainment
8:00–11:00 PM Cash Bar President's Hall
Thursday, February 22, 2024
7:00–11:59 PM Departure