| 4:00–8:00 PM | Registration | Riverview Lounge |
| 6:00–8:00 PM | Welcome Mixer | Riverview Lounge |
| 7:00–8:00 AM | Breakfast | Alberta/New Brunswick |
| 8:00–9:00 AM | Welcome and Keynote Address (Joint) | Cascade Ballroom |
| * Karen Adelman, Harvard Medical School Session Chair |
| Patrick Cramer, Max Planck Institute for Multidisciplinary Sciences Chromatin and Transcription |
| 9:00–11:30 AM | Mechanisms of Gene Control and Epigenetic Regulation (Joint) | Cascade Ballroom |
| * Seychelle Vos, Massachusetts Institute of Technology Session Chair |
| Dirk Schübeler, Friedrich Miescher Institute for Biomedical Research Controlling CpG islands |
| François Fuks, University of Brussels RNA Modifications in Health and Disease |
| Lacramioara Bintu, Stanford University High-Throughput Measurements of Activation and Repression Domains from Human Proteins |
| Havva Ortabozkoyun, University of Miami / HHMI Short Talk: Members of an Array of Zinc Finger Proteins Specify Distinct Hox Chromatin Boundaries |
| 9:30–9:50 AM | Coffee Break | Riverview Lounge |
| 9:50–9:55 AM | Award Recipient Acknowledgement | Cascade Ballroom |
| 11:30–1:00 PM | Poster Setup | Alberta/New Brunswick |
| 11:30–2:30 PM | On Own for Lunch |
| 1:00–10:00 PM | Poster Viewing | Alberta/New Brunswick |
| 2:30–4:30 PM | Symposia Spotlight 1: Research presentations selected from abstract submissions | Alhambra |
| * Luca Giorgetti, Friedrich Miescher Institute for Biomedical Research Session Chair |
| Julia Schaepe, Stanford University Thermodynamic Principles Link in vitro Transcription Factor Affinities to Single-molecule Chromatin States in Cells |
| Allison James, Harvard Medical School Structural Basis of Human CHD1 Nucleosome Recruitment and Pausing |
| Blaine Bartholomew, MD Anderson Cancer Center SWI/SNF Regulates Nuclear Condensates in an eRNA Dependent Manner |
| Zachary A Drum, University of North Carolina at Chapel Hill Mechanisms of Phase-separation Driven Chromatin Looping in Acute Myeloid Leukemia |
| James Kentro, Brown University Conserved Transcription Factors Coordinate Synaptic Gene Expression Through Repression |
| Daniel Ibrahim, Berlin Institute of Health Enhancer-promoter Specificity Mediated by the Promoter-proximal Region |
| Wen Yan, Pfizer Identification Of A Selective And Orally Bioavailable BPTF PROTAC With Anti-Tumor Activity In SWI/SNF Mutant Lung Cancer |
| 4:30–5:00 PM | Coffee Break with Hot Chocolate, Firepits & Mountain Views | Conservatory Terrace |
| 5:00–6:45 PM | Enhancer-Promoter Communication | Alhambra |
| * Lacramioara Bintu, Stanford University Session Chair |
| Thomas G Graham, University of California, Berkeley Single-molecule Live Imaging of Transcriptional Regulatory Complex Interactions using Proximity-assisted Photoactivation (PAPA) |
| Aukje Marieke Oudelaar, Max Planck Institute for Multidisciplinary Science Regulation of Gene Expression in the 3D Genome |
| Luca Giorgetti, Friedrich Miescher Institute for Biomedical Research Dynamics of Chromatin Loops and the Consequence on Transcription |
| Mervenaz Koska, Stanford University Short Talk: Understanding the Mechanism of Promoter Competition |
| 7:00–8:00 PM | Social Hour with Lite Bites | Alberta/New Brunswick |
| 7:30–10:00 PM | Poster Session 1 | Alberta/New Brunswick |
| 7:00–8:00 AM | Breakfast | Alberta/New Brunswick |
| 8:00–11:00 AM | Mechanisms of Chromatin Transcription | Alhambra |
| * Xavier Darzacq, University of California, Berkeley Session Chair |
| Yanhui Xu, Fudan University Structural Basis of Transcription Initiation on Chromatin |
| Stephen Buratowski, Harvard Medical School Single molecule microscopy reveals unexpected features of RNApII transcription |
| Karen Arndt, University of Pittsburgh Chromatin and Transcription Elongation |
| Carl Wu, Johns Hopkins University The biogenesis and regulation of chromatin accessibility for dynamic transcription complexes |
| Sarah Hainer, University of Pittsburgh Short Talk: Widespread Impact of Nucleosome Remodelers on Transcription at Cis-regulatory Elements |
| Michael J Guertin, UConn Health Short Talk: Mechanisms of Direct cis Repression by a Transcriptional Activator |
| 9:00–9:20 AM | Coffee Break | Riverview Lounge |
| 11:00–1:00 PM | Poster Setup | Alberta/New Brunswick |
| 11:00–5:00 PM | On Own for Lunch |
| 1:00–2:30 PM | Career Roundtable (Joint) | Alhambra |
| Paola Scaffidi, European Institute of Oncology Group Leader |
| Gromek Smolen, Foghorn Therapeutics VP, Head of Biology |
| Evan J. Worden, Van Andel Institute Assistant Professor |
| Michael S Werner, University of Utah Assistant Professor |
| Ivanka D Kamenova, Nature Protocols Senior Editor |
| 1:00–10:00 PM | Poster Viewing | Alberta/New Brunswick |
| 4:30–5:00 PM | Coffee Available | Riverview Lounge |
| 5:00–7:00 PM | Mechanisms and Dynamics of Genome Folding | Alhambra |
| * Jennifer E. Phillips-Cremins, University of Pennsylvania Session Chair |
| Tineke L Lenstra, Netherlands Cancer Institute The Kinetics of Transcription Factor Target Search and Activation in Live Cells |
| Xavier Darzacq, University of California, Berkeley Quantifying the Molecular Transactions that Control Transcription in Live Cells |
| Jennifer E. Phillips-Cremins, University of Pennsylvania Genome Looping and its Consequences on Transcription |
| Noura Maziak, Imperial College; LMS MRC Short Talk: Extensive 3D Genome Reorganization Foreshadows Zygotic Genome Activation in Drosophila |
| Erika Anderson, UCSF Short Talk: Enhancers Regulate Transcription without Acting as Loading Sites for Extruding Cohesin |
| 7:00–8:00 PM | Social Hour with Lite Bites | Alberta/New Brunswick |
| 7:30–10:00 PM | Poster Session 2 | Alberta/New Brunswick |
| 7:00–8:00 AM | Breakfast | Alberta/New Brunswick |
| 8:00–11:00 AM | Pausing Dynamics/Transcription Termination | Alhambra |
| * Karen Arndt, University of Pittsburgh Session Chair |
| Roberto Vazquez Nunez, Massachusetts Institute of Technology Short Talk: Remote Presenter - GATO-Seq Uncovers RNA Polymerase II Promoter-Proximal Pausing Dynamics |
| John T. Lis, Cornell University The Regulatory Interplay of Enhancers, Facilitators, and Promoters – A Case Study in a Native Chromatin Context |
| Seychelle Vos, Massachusetts Institute of Technology Pausing and Release into Productive Elongation |
| Lidia Vasilieva, University of Oxford Kinases, Phosphatases and their Role in Transcription Termination |
| Benjamin R Sabari, University of Texas Southwestern Medical Center Short Talk: Gain-of-function RNA Polymerase II Partitioning is a Shared Feature of Diverse Oncogenic Fusions |
| William Lai, Cornell University Short Talk: High-resolution Mapping of the Pol II and Pol III Regulatory Complexes under Transcriptional Perturbation |
| Katerina Kraft, Stanford Short Talk: Enhancer Activation from Transposable Elements in Extrachromosomal DNA |
| 9:15–9:35 AM | Coffee Break | Riverview Lounge |
| 11:00–2:30 PM | On Own for Lunch |
| 2:30–4:15 PM | Symposia Spotlight 2: Research presentations selected from abstract submissions | Alhambra |
| * John T. Lis, Cornell University Session Chair |
| Kalon J Overholt, MIT High-resolution Footprints in Chromatin Architecture Enable Discovery of Transcription Factor Nano-assemblies |
| Michael Quezada, Harvard Medical School High-throughput Characterization of Interactions between Transcription Factors and Intrinsically Disordered Regions with Optical Pooled Screening |
| David Gross, Louisiana State University Health Sciences Center Identification of Regulators that Drive Dynamic, Heat Shock-Induced Genome Restructuring |
| Katherine Fleck, University of Connecticut Novel Gene Evolution and 3D Chromatin Organization |
| Matt Franklin, Stanford University Human Satellite 3 DNA Encodes Megabase-scale Transcription Factor Binding Platforms |
| Djem Kissiov, University of California, Berkeley Decoupling Transcriptional Memory from Chromatin Structure through Analysis of Single Chromatin Fibers |
| 4:30–5:00 PM | Coffee Available | Riverview Lounge |
| 5:00–5:45 PM | Keynote Address (Joint) | Cascade Ballroom |
| * Seychelle Vos, Massachusetts Institute of Technology Session Chair |
| Yang Shi, Ludwig Institute for Cancer Research, Oxford Branch Chromatin Regulation and Cancer |
| 5:45–7:15 PM | Transcription and Epigenetics in Disease (Joint) | Cascade Ballroom |
| * Kristian Helin, The Institute of Cancer Research Session Chair |
| Paola Scaffidi, European Institute of Oncology Epigenetics and Functional Intratumor Heterogeneity |
| Gromek Smolen, Foghorn Therapeutics Targeting Chromatin Modulators with Therapeutic Degraders |
| Tony Kouzarides, Gurdon Institute, University of Cambridge Targeting RNA Modifying Enzymes in the Treatment of Cancer |
| 7:15–7:30 PM | Meeting Wrap-Up: Outcomes and Future Directions (Organizers) (Joint) | Cascade Ballroom |
| 7:30–8:30 PM | Social Hour with Lite Bites | Alberta/New Brunswick |
| 12:00–11:59 PM | Departure |