| 4:00–8:00 PM | Registration | Macdonald Foyer |
| 6:00–8:00 PM | Welcome Mixer | Macdonald Foyer |
| 7:00–8:00 AM | Breakfast | Woodlands Terrace |
| 7:30–8:00 AM | Poster Setup | Macdonald EF |
| 7:30–7:00 PM | Poster Viewing | Macdonald EF |
| 8:00–9:45 AM | Welcome and Keynote Session (Joint) | Macdonald ABCD |
| * Jose Ordovas-Montanes, Boston Children's Hospital and Harvard Medical School Session Chair |
| * Quinton Smith, University of California, Irvine Session Chair |
| Matthew F Krummel, University of California, San Francisco Tissue Archetypes Across Space and Time |
| Gordana Vunjak-Novakovic, Columbia University Organs-on-Chip Models for Studying Human Pathophysiology |
| 9:45–10:15 AM | Coffee Break | Macdonald Foyer |
| 10:15–10:20 AM | Award Recipient Acknowledgement | Macdonald ABCD |
| 10:20–11:30 AM | High-Throughput Approaches to Model Cells and Tissues (Joint) | Macdonald ABCD |
| * Chrysothemis Brown, Sloan Kettering Institute Session Chair |
| * Quinton Smith, University of California, Irvine Session Chair |
| Dana Pe'er, Memorial Sloan Kettering Cancer Center Plasticity in the Tissue Context |
| Peter Winter, Broad Institute Defining, Modeling, and Targeting Cell States in Cancer |
| 11:30–12:30 PM | Lunch | Woodlands Terrace |
| 12:00–2:30 PM | Poster Session 1 | Macdonald EF |
| 2:30–4:30 PM | Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions | MacDonald CD |
| * Quinton Smith, University of California, Irvine Session Chair |
| Oscar J. Abilez, Stanford University Perfusion Of Human Cardiac Vascularized Organoids |
| Meghan Capeling, Genentech Dictionary Of Human Intestinal Organoid Responses to Secreted Niche Factors at Single Cell Resolution |
| Alexander Kleger, Institute of Molecular Oncology and Stem Cell Biology, Ulm University 3D Bioprinting Leverages Mature Pancreatic Ductal Tube Formation and Advances Early-Stage Cancer Modelling |
| Jessica Klein, Genentech The Differentiation State of Small Intestinal Organoid Models Influences Prediction of Drug-Induced Toxicity |
| Alison P. McGuigan, University of Toronto Engineered Tumours Containing Patient Derived Pancreatic Organoids and Primary Macrophages To Dissect The Relative Impact Of Multiple Tumour Microenvironmental Signals on Tumour Cell Behaviour |
| M. Carmen Ortuño Costela, Berlin Institute of Health at Charité Generation Of Hepatocyte Organoids From Primary Hepatocytes |
| Chris Yankaskas, Thermo Fisher Scientific Derivation Of a Cohort Of Patient-Derived Cancer Organoids for Screening Immunotherapy Efficacy |
| Tobias Raabe, University of Pennsylvania Lipid Nanoparticles For Rapid Cell Type Specific Genome Editing Of A MASH Patient Liver Derived 3D Fibrosis Model |
| 4:30–5:00 PM | Coffee Available | Macdonald Foyer |
| 5:00–7:00 PM | Controlling the Organoid Microenvironment | MacDonald CD |
| Celeste M Nelson, Princeton University Mechanical Drivers of Lung Development |
| * Alex Hughes, University of Pennsylvania Engaging the Design Cycle of Rhythmic Stem Cell Biology in Developing and Synthetic Kidney Tissues |
| Pilnam Kim, Korea Advanced Institute of Science and Technology ECM Control of Organoid Fate |
| * Matthias Lutolf, Roche Institute of Human Biology and EPFL Modeling Tumor–Microenvironment Crosstalk in Bioengineered Organoids |
| 7:00–8:00 PM | On Own for Dinner |
| 7:00–8:00 AM | Breakfast | Woodlands Terrace |
| 8:00–11:00 AM | Reverse Engineering Embryogenesis | MacDonald CD |
| Margherita Y Turco, Friedrich Miescher Institute Organoid Models to Investigate Maternal-Fetal Interactions in Human Pregnancy |
| Jared Toettcher, Princeton University Gastruloid Patterning |
| * Quinton Smith, University of California, Irvine Microfluidic Models of Vascularization |
| * Xihe Liu, Johns Hopkins University Short Talk: Gastrulation-Stage Cells Can Self-Organize and Pattern the Body Via Slit/Robo Signaling |
| Elizabeth Wayne, University of Washington Monocytes and Macrophages Incorporated Lung Airway Organoids |
| 9:00–9:20 AM | Coffee Break | Macdonald Foyer |
| 11:00–1:00 PM | Poster Setup | Macdonald EF |
| 11:00–3:00 PM | On Own for Lunch |
| 1:00–10:00 PM | Poster Viewing | Macdonald EF |
| 1:30–2:45 PM | Career Roundtable (Joint) | MacDonald CD |
| Oscar J. Abilez, Stanford University Senior Scientist-Stanford & Co-Founder-Bullseye Biotechnologies |
| Giuliana Rossi, Roche Institute of Human Biology Senior Scientist |
| Lei Tang, Nature Methods Senior Editor |
| 3:00–4:30 PM | Advances in Single Cell Biology and Organoids for Precision Medicine (Joint) | Macdonald AB |
| * Quinton Smith, University of California, Irvine Session Chair |
| * Jose Ordovas-Montanes, Boston Children's Hospital and Harvard Medical School Session Chair |
| Oshiomah Oyageshio, University of California Davis Remote Presentation: Integrating Single Cell Multiomics and Ancestry to Investigate TB susceptibility |
| Joshua De Sousa Casal, Boston Children's Hospital Early Life Development of The Pediatric Duodenum Across Distinct Geographical Environments |
| Kaitriana Colling, University of Iowa Lead Compound Identification Using Live-Cell Imaging of Patient-Derived Endometrial Cancer Organoids |
| Hyung-Sik Kim, Pusan National University TGFβ2-Driven Iron Dysregulation and Ferroptosis in Salivary Glands Trigger Hyposalivation Under Postmenopausal Conditions |
| Gat Rauner, Tufts University School of Medicine Next-Generation Breast Organoids as a Platform for Studying Human Lactation and Breast Tissue Regeneration |
| 4:30–5:00 PM | Coffee Available | Macdonald Foyer |
| 5:00–7:00 PM | Organoid Vascularization | MacDonald CD |
| Kelly R. Stevens, University of Washington Deploying 3D Printing to Vascularize Organoids |
| * Britta Trappmann, TU Dortmund University Vascularization of Organoids in Synthetic Extracellular Matrices |
| Clement Quintard, University of British Columbia Short Talk: Engineering Organoids-On-Chip With Flow Dynamics To Model Organ-Specific Vascularization And Immune-Enhanced Cellular Cross-Talk In Cardiac Tissues |
| * Mingxia Gu, UCLA Short Talk: Reconstructing Organ-Specific Vasculature In iPSC-Derived Lung And Intestinal Organoids |
| Giuliana Rossi, Roche Institute of Human Biology Short Talk: Improved Human Gastruloids as Templates for Complex Organogenesis |
| 7:00–8:00 PM | Social Hour with Lite Bites | Woodlands Terrace |
| 7:30–10:00 PM | Poster Session 2 | Macdonald EF |
| 7:00–8:00 AM | Breakfast | Woodlands Terrace |
| 8:00–11:00 AM | Programmable Organoids | MacDonald CD |
| Anne Grapin-Botton, Max Planck Institute of Molecular Cell Biology and Genetics Remote Presentation: High Content Screening in Human Pancreatic Organoids |
| Martin Fussenegger, ETH Zürich Remote Control of Cellular Behavior |
| Karmella Haynes, Emory University and Georgia Institute of Technology Controlling Chromatin Epigenetics in 3D Breast Cancer Spheroids |
| Sachin N Davis, University of Pennsylvania Short Talk: Engineering Optogenetic Control of Anisotropic Strain for Sculpting Epithelial Morphogenesis |
| Louis S Prahl, University of Pennsylvania Short Talk: Synthetic Control of Epithelial Morphogenesis by RET Receptor Tyrosine Kinase |
| * Michael Blatchley, Syracuse University Short Talk: Spatiotemporally Controlled Matrix Softening Facilitates Deterministic Crypt Formation In iPSC- Derived Intestinal Organoids |
| * Steven Caliari, University of Virginia Short Talk: Spatiotemporal Control of Hydrogel Stress Relaxation for Creating Viscoelastic 3D Cell Culture Microenvironments |
| 9:00–9:20 AM | Coffee Break | Macdonald Foyer |
| 9:20–9:25 AM | People's Choice Poster Award Announcement | MacDonald CD |
| 11:00–3:00 PM | On Own for Lunch |
| 3:00–4:30 PM | Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions | MacDonald CD |
| * Quinton Smith, University of California, Irvine Session Chair |
| Marianna Kruithof-de Julio, Universität Bern - Bladder Cancer-On-Chip: A 3D Model To Study Human Urothelial Tumors Under Physiological Stretch |
| Madelyn Arzt, Cedars-Sinai Medical Center Protein-Encapsulated Doxorubicin Reduces Cardiotoxicity In Hipsc-Cardiac Spheroids While Maintaining Anticancer Efficacy |
| Martin Stahl, STEMCELL Technologies IntestiCult™ Plus Organoid Growth Medium Provides A Novel Means Of Establishing And Maintaining Physiologically-Relevant Intestinal Organoids |
| Samrawit Aforki, abbvie Development of a Complex Human Skin Model to Investigate the Impact of Therapeutic Intervention on Vicious Cycle of Atopic Dermatitis |
| Joram Mooiweer, University Medical Center Groningen Advanced Intestine-On-Chip And Immuno-Organoid Models To Study Intestinal Diseases And Test Novel Treatments |
| Jyoti Rao, Institute of Human Biology Single Lumen Neuroepithelial Cyst-Derived Neural Organoids |
| 4:30–5:00 PM | Coffee Available | Macdonald Foyer |
| 5:00–6:15 PM | Physical Principles of Tissue Morphogenesis | MacDonald CD |
| Xavier Trepat, Institute for Bioengineering of Catalonia Mechanobiology of Intestinal Organoids |
| * Austin J Graham, University of California, San Francisco Living Materials Promote the Self-Organization of More Complex and Reproducible Organoid Models |
| * Martina Celotti, Hubrecht institute Short Talk: Distinct Mutational Oncogenic Combinations, introduced by CRISPR in human basal airway Organoids, Drive the Emergence of Small Cell or Non-Small Cell Lung Cancer. |
| 6:15–6:30 PM | Meeting Wrap-Up: Outcomes and Future Directions and Survey (Organizers) | MacDonald CD |
| 6:30–8:00 PM | Social Hour with Lite Bites | Woodlands Terrace |
| 12:00–11:59 PM | Departure |