Adipose Tissue: From Cellular Mechanisms to Systemic Health (Z3)
March 21-24, 2027  | Fairmont Banff Springs, Banff, AB, Canada
Kirsty L. Spalding, Camilla C Schéele and Clair Crewe
* Session Chair † Invited but not yet accepted | Program current as of October 12, 2025 9 PM | For the most up-to-date details, visit https://www.keystonesymposia.org
Sunday, March 21, 2027
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Monday, March 22, 2027
7:00–8:00 AM Breakfast
8:00–9:30 AM Welcome and Keynote Session (Joint)
  Daniel J. Drucker †, Lunenfeld-Tanenbaum Research Institute
Incretin Overview; MoA to Weight Control and Benefits to Other Common Associated Diseases
 
  Philipp E. Scherer †, University of Texas Southwestern Medical Center
Role of Adipose Tissue in Incretin-Based Therapeutics
 
9:30–9:50 AM Coffee Break
9:30–11:15 AM Incretins and Adipose Tissue Biology (Joint)
  Jeffrey M. Friedman †, Rockefeller University
Integration of Hedonic and Homeostatic Weight Control
 
  Samuel Klein †, Washington University School of Medicine
Metabolic Adaptation after Pharmacological Weight Loss
 
  Short Talk(s) Chosen from Abstracts
 
11:15–12:15 PM Meet the Editors (Joint)
12:15–1:00 PM Poster Setup
12:15–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1: Late-Breaking Adipocyte Biology Research
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Adipose Tissue Extracellular Vesicles as a Novel Therapeutic Target
  Clair Crewe, Washington University School of Medicine in St. Louis
Adipocyte Extracellular Vesicles in Cardiometabolic Disease
 
  Yan Bi †, Nanjing University
Adipocyte Extracellular Vesicles in the Central Regulation of Obesity
 
  C. Ronald Kahn †, Joslin Diabetes Center and Harvard Medical School
Extracellular miRNAs as Mediators of Obesity-Associated Disease
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Tuesday, March 23, 2027
7:00–8:00 AM Breakfast
8:00–11:00 AM Emerging Insights into Adipose Tissue and Incretin Pharmacology (Joint)
  Ruth E. Gimeno †, Eli Lilly and Company
Incretin Therapies for Combating Neurodegeneration and Addiction
 
  Matthias Blüher †, University of Leipzig
Novel Horizons for Liver and Kidney Health: Translating Incretin Research into Organ-Specific Therapies
 
  Silvia Corvera †, University of Massachusetts Medical School
Therapeutic Targeting of Adipose Depots
 
  Tore Bengtsson †, Stockholm University
Using Highly Selective β2-Agonists for the Treatment of Obesity, Diabetes and Age-Related Muscle Loss
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–12:00 PM Panel Discussion: The Future of Incretin Therapeutics: Scientific Impact, Clinical Challenges, and Shaping Public Understanding of Obesity (Joint)
11:00–1:00 PM Poster Setup
11:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
3:00–4:30 PM Career Roundtable
4:30–5:00 PM Coffee Available
5:00–7:00 PM Adipose Tissue and Cancer
  Kirsty L. Spalding, Karolinska Institute
Adipocyte Senescence and Breast Cancer in Humans
 
  Catherine Muller †, University of Toulouse
The Contribution of Cancer-Associated Adipocytes in Breast Cancer
 
  Nadav Ahituv †, University of California, San Francisco
Starving Tumors with Fat
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Wednesday, March 24, 2027
7:00–8:00 AM Breakfast
8:00–11:00 AM Brown and White Adipose Tissue Interactions with the Immune System
  Jonathan R. Brestoff †, Washington University in St. Louis
Mitochondria Transfer and Adipose Immunometabolism
 
  Camilla C Schéele, University of Copenhagen
Transcriptional Rewiring of Brown Adipose Progenitors from Adipogenic to Inflammatory States
 
  Farnaz Shamsi †, New York University
Macrophages Derived Factors Drive Neurovascular Expansion and Thermogenesis in Brown Adipose Tissue?
 
  Gökhan S. Hotamisligil †, Harvard School of Public Health
Interactions between Adipose Innate Immune Defense and Infection
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–5:00 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: Emerging Technologies in Adipose Tissue Modelling
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM Evolutionary Perspectives on Adipose Function
  Soren Nielsen †, Rigshospitalet
Adipose Tissue Capacity and Adaptation in Hibernating Brown Bears
 
  Martin Jastroch †, Stockholm University
Evolution of Mammalian Adipose Tissue Thermogenesis
 
  Shingo Kajimura †, Harvard Medical School, Beth Israel Deaconess Medical Center
Alternative Evolutionary Paths of Adipose Tissue in Fish
 
  Short Talk(s) Chosen from Abstracts
 
6:00–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Thursday, March 25, 2027
12:00–11:59 PM Departure