Incretin Biology and Therapeutics: Transforming Obesity and Associated Diseases (Z4)
March 21-24, 2027
| Fairmont Banff Springs, Banff, AB, Canada
Zach Gerhart-Hines, Richard D DiMarchi and Fiona M. Gribble
| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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| 8:00–9:30 AM |
Welcome and Keynote Session (Joint) |
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Daniel J. Drucker †, Lunenfeld-Tanenbaum Research Institute
Incretin Overview; MoA to Weight Control and Benefits to Other Common Associated Diseases |
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Philipp E. Scherer †, University of Texas Southwestern Medical Center
Role of Adipose Tissue in Incretin-Based Therapeutics |
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| 9:30–9:50 AM |
Coffee Break |
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| 9:30–11:15 AM |
Incretins and Adipose Tissue Biology (Joint) |
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Jeffrey M. Friedman †, Rockefeller University
Integration of Hedonic and Homeostatic Weight Control |
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Samuel Klein †, Washington University School of Medicine
Metabolic Adaptation after Pharmacological Weight Loss |
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Short Talk(s) Chosen from Abstracts
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| 11:15–12:15 PM |
Meet the Editors (Joint) |
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| 12:15–1:00 PM |
Poster Setup |
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| 12:15–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Symposia Spotlight 1: New Advances in Incretins or Novel MoAs with Therapeutic Potential |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Peripheral versus Central Incretin Action on Homeostasis |
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Timo D Müller †, Helmholtz Munich
GIP Agonism in the Brain and Periphery |
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Murielle M Véniant-Ellison †, Amgen Inc.
GIP Antagonism as a Therapeutic Approach |
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Ryan J. Watts †, Denali Therapeutics Inc
Deep Brain Action of Incretin Agonists: Potential Opportunities and Risks |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Emerging Insights into Adipose Tissue and Incretin Pharmacology (Joint) |
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Ruth E. Gimeno †, Eli Lilly and Company
Incretin Therapies for Combating Neurodegeneration and Addiction |
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Matthias Blüher †, University of Leipzig
Novel Horizons for Liver and Kidney Health: Translating Incretin Research into Organ-Specific Therapies |
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Silvia Corvera †, University of Massachusetts Medical School
Therapeutic Targeting of Adipose Depots |
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Tore Bengtsson †, Stockholm University
sing Highly Selective β2-Agonists for the Treatment of Obesity, Diabetes and Age-Related Muscle Loss |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–12:00 PM |
Panel Discussion: The Future of Incretin Therapeutics: Scientific Impact, Clinical Challenge (Joint) |
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| 11:00–1:00 PM |
Poster Setup |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 3:00–4:30 PM |
Career Roundtable |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Gut-Brain Signaling in Food Preference, Satiety, and Behavior |
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Fiona M. Gribble, University of Cambridge
Endocrine Signaling in the Gut-Brain Axis |
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Lora K. Heisler †, Rowett Institute, University of Aberdeen
Uncovering Nonaversive Brain Circuits that Control Feeding |
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Henning Fenselau †, University of Cologne
Homeostatic Feeding Circuits |
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Amber L. Alhadeff †, Monell Chemical Senses Center
Neural Circuits Regulating Food Intake and Motivation |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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Wednesday, March 24, 2027
| 8:00–11:00 AM |
Beyond Incretins - Newer Players |
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Richard D DiMarchi, Indiana University
Chemistry to Enable Greater Efficacy, Safety, and Convenience |
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Paul M. Titchenell †, Eli Lilly
Clinical Development of Targets for Lean Mass Preservation |
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Kirsten Raun †, Novo Nordisk A/S
Amylin Mono- and Polyagonists for Metabolic Diseases |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 2:30–4:30 PM |
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–6:45 PM |
Beyond Incretins – Unmet Therapeutic Needs |
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Zach Gerhart-Hines, University of Copenhagen
Energy Expenditure Targets |
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Manu Chakravarthy †, Roche
Small Molecule Agonists/Biased Agonism |
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Ania Jastreboff †, Yale University
Clinical Perspective of Unmet Needs |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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